1
ALPL-Bergrennen 70er Jahre
ALPL-Bergrennen 70er Jahre
DATE: 2013/04/15::
2
ALPL-Bergrennen 1984
ALPL-Bergrennen 1984
DATE: 2013/04/14::
3
Faschingssitzung der Faschingsgilde Alpl 2014
Faschingssitzung der Faschingsgilde Alpl 2014
DATE: 2014/01/15::
4
Brechten - Alpl 12.01.2014
Brechten - Alpl 12.01.2014
DATE: 2014/01/14::
5
Volvo V40 vs  Alpl
Volvo V40 vs Alpl
DATE: 2014/12/27::
6
Harrys liabste Hütt
Harrys liabste Hütt'n Alpl Joglland
DATE: 2012/09/19::
7
Alpl 28.03.2015
Alpl 28.03.2015
DATE: 2015/03/29::
8
Waldheimat Alpl
Waldheimat Alpl
DATE: 2012/09/19::
9
Schitour Inzinger Alpl - Brechten
Schitour Inzinger Alpl - Brechten
DATE: 2015/02/12::
10
ALPL ( Suara si cantik Aira Yudhoyono )
ALPL ( Suara si cantik Aira Yudhoyono )
DATE: 2013/12/05::
11
S6 Autobahn Krieglach nach Waldheimat Alpl (Zinkhaus FEWO)
S6 Autobahn Krieglach nach Waldheimat Alpl (Zinkhaus FEWO)
DATE: 2013/12/09::
12
Hofer Alpl Südtirol
Hofer Alpl Südtirol
DATE: 2012/06/17::
13
Sturmtief "Andrea" fegt übers Alpl
Sturmtief "Andrea" fegt übers Alpl
DATE: 2012/01/14::
14
MGF 07.05.2011 Alpl
MGF 07.05.2011 Alpl
DATE: 2011/05/07::
15
Illinois Stories | Treasures of the ALPL | WSEC-TV/PBS Springfield
Illinois Stories | Treasures of the ALPL | WSEC-TV/PBS Springfield
DATE: 2014/11/06::
16
Prinzenpaarvorstellung der Faschingsgilde Alpl 2013
Prinzenpaarvorstellung der Faschingsgilde Alpl 2013
DATE: 2013/11/07::
17
Motorradausflug Alpl 29 06 2013
Motorradausflug Alpl 29 06 2013
DATE: 2013/06/29::
18
Gasthof Alpl Hotel - Sirnitz - Austria
Gasthof Alpl Hotel - Sirnitz - Austria
DATE: 2014/04/13::
19
Alpl Schikurs 2013
Alpl Schikurs 2013
DATE: 2013/01/17::
20
James Cottriall Alpl 2011
James Cottriall Alpl 2011
DATE: 2011/01/06::
21
Ducati Hypermotard 821, Alpl + Zufahrt
Ducati Hypermotard 821, Alpl + Zufahrt
DATE: 2014/11/01::
22
Roseggerhof TV -  Christmettenweg in Peter Rosegger´s Waldheimat - Alpl
Roseggerhof TV - Christmettenweg in Peter Rosegger´s Waldheimat - Alpl
DATE: 2009/01/10::
23
Flaurling, jakobs alpl 2
Flaurling, jakobs alpl 2
DATE: 2013/01/28::
24
fazer2010 alpl steiermark
fazer2010 alpl steiermark
DATE: 2010/10/29::
25
Dolomite Alphorn Concert at Tierser Alpl Alpine Refuge
Dolomite Alphorn Concert at Tierser Alpl Alpine Refuge
DATE: 2010/07/29::
26
Tierser Alpl Hütte
Tierser Alpl Hütte
DATE: 2011/08/14::
27
Knottenkonzert mit Heidi Pixner beim Tierser Alpl
Knottenkonzert mit Heidi Pixner beim Tierser Alpl
DATE: 2011/08/10::
28
Luca Alpl
Luca Alpl'K Part
DATE: 2014/03/18::
29
Conférence de presse de l
Conférence de presse de l'ALPL et du LCGB-SEA "Lutte contre la fatigue des pilotes (3 octobre 2012)
DATE: 2012/10/04::
30
2015 Ausztria, Alpl az alpannonia főtúrautvonalon
2015 Ausztria, Alpl az alpannonia főtúrautvonalon
DATE: 2015/04/24::
31
1.Rosegger Wirtshaus-Singen auf dem Alpl im GH Roseggerhof
1.Rosegger Wirtshaus-Singen auf dem Alpl im GH Roseggerhof
DATE: 2013/10/14::
32
Hofer Alpl
Hofer Alpl
DATE: 2012/06/17::
33
Peter Roseggers Waldschule in Alpl. Steiermark
Peter Roseggers Waldschule in Alpl. Steiermark
DATE: 2008/10/21::
34
alpl richtung ratten
alpl richtung ratten
DATE: 2014/11/15::
35
mematvo.at - KW 31 - Jakob der Letzte am Alpl
mematvo.at - KW 31 - Jakob der Letzte am Alpl
DATE: 2013/08/06::
36
Pilgerweg vom Alpl bis Gh. Postmühle  Teil 3
Pilgerweg vom Alpl bis Gh. Postmühle Teil 3
DATE: 2013/07/28::
37
Wanderung aufs Alpl .-
Wanderung aufs Alpl .-
DATE: 2012/11/25::
38
hermann alpl 2
hermann alpl 2
DATE: 2014/12/18::
39
Bruggraber"s Familienurlaub für sommer und winter Waldheimathof Alpl getestet
Bruggraber"s Familienurlaub für sommer und winter Waldheimathof Alpl getestet
DATE: 2011/08/16::
40
From te balcony Gasthof ALPL
From te balcony Gasthof ALPL
DATE: 2010/01/23::
41
Alpl  2011
Alpl 2011
DATE: 2011/02/16::
42
Schitag Alpl
Schitag Alpl
DATE: 2011/02/25::
43
Airtel Lanka | ALPL Logo Launch (Internal Event) by D STUDIO CMB
Airtel Lanka | ALPL Logo Launch (Internal Event) by D STUDIO CMB
DATE: 2012/07/06::
44
James Cottriall - Unbreakable meets Johnny Cash (Zugabe), Alpl, 08.08.2010
James Cottriall - Unbreakable meets Johnny Cash (Zugabe), Alpl, 08.08.2010
DATE: 2010/08/09::
45
Snowboard on Alpl
Snowboard on Alpl
DATE: 2008/02/05::
46
ALPL
ALPL
DATE: 2014/04/10::
47
Angelos Touren: Schneeschuh Alpl - Stanglalm
Angelos Touren: Schneeschuh Alpl - Stanglalm
DATE: 2014/02/23::
48
alpl 2013
alpl 2013
DATE: 2013/12/28::
49
Chrisrmettengang 24.12.2013 Alpl Kluppeneggerhof  Peter Rosegger
Chrisrmettengang 24.12.2013 Alpl Kluppeneggerhof Peter Rosegger
DATE: 2013/12/26::
50
Behind The Scenes at ALPL -- Technical Services
Behind The Scenes at ALPL -- Technical Services
DATE: 2009/02/24::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Alkaline phosphatase, liver/bone/kidney
Identifiers
Symbols ALPL ; AP-TNAP; APTNAP; HOPS; TNAP; TNSALP
External IDs OMIM171760 MGI87983 HomoloGene37314 ChEMBL: 5979 GeneCards: ALPL Gene
EC number 3.1.3.1
RNA expression pattern
PBB GE ALPL 215783 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 249 11647
Ensembl ENSG00000162551 ENSMUSG00000028766
UniProt P05186 P09242
RefSeq (mRNA) NM_000478 NM_001287172
RefSeq (protein) NP_000469 NP_001274101
Location (UCSC) Chr 1:
21.84 – 21.9 Mb
Chr 4:
137.74 – 137.8 Mb
PubMed search [1] [2]

Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene.[1][2]

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on chromosome 2, whereas the tissue-nonspecific form is located on chromosome 1. The product of this gene is a membrane-bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization. However, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation, since this determines age of onset and severity of symptoms.[3]

References[edit]

  1. ^ Weiss MJ, Henthorn PS, Lafferty MA, Slaughter C, Raducha M, Harris H (Oct 1986). "Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase". Proc Natl Acad Sci U S A 83 (19): 7182–6. doi:10.1073/pnas.83.19.7182. PMC 386679. PMID 3532105. 
  2. ^ Swallow DM, Povey S, Parkar M, Andrews PW, Harris H, Pym B, Goodfellow P (May 1988). "Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1". Ann Hum Genet 50 (Pt 3): 229–35. doi:10.1111/j.1469-1809.1986.tb01043.x. PMID 3446011. 
  3. ^ "Entrez Gene: ALPL alkaline phosphatase, liver/bone/kidney". 

External links[edit]

Further reading[edit]


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