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1
ALPL-Bergrennen 70er Jahre
ALPL-Bergrennen 70er Jahre
::2013/04/15::
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2
Motorradausflug Alpl 29 06 2013
Motorradausflug Alpl 29 06 2013
::2013/06/29::
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3
ALPL-Bergrennen 1984
ALPL-Bergrennen 1984
::2013/04/14::
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4
Faschingssitzung der Faschingsgilde Alpl 2014
Faschingssitzung der Faschingsgilde Alpl 2014
::2014/01/15::
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5
Tierser Alpl Hütte
Tierser Alpl Hütte
::2011/08/14::
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6
Waldheimat Alpl
Waldheimat Alpl
::2012/09/19::
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7
1.Rosegger Wirtshaus-Singen auf dem Alpl im GH Roseggerhof
1.Rosegger Wirtshaus-Singen auf dem Alpl im GH Roseggerhof
::2013/10/14::
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8
Hofer Alpl Südtirol
Hofer Alpl Südtirol
::2012/06/17::
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9
Sturmtief "Andrea" fegt übers Alpl
Sturmtief "Andrea" fegt übers Alpl
::2012/01/14::
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10
S6 Autobahn Krieglach nach Waldheimat Alpl (Zinkhaus FEWO)
S6 Autobahn Krieglach nach Waldheimat Alpl (Zinkhaus FEWO)
::2013/12/09::
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11
Bruggraber"s Familienurlaub für sommer und winter Waldheimathof Alpl getestet
Bruggraber"s Familienurlaub für sommer und winter Waldheimathof Alpl getestet
::2011/08/16::
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12
●Tierser AlplからRif PlattkofelHutte・・6月20日YouTube
●Tierser AlplからRif PlattkofelHutte・・6月20日YouTube
::2014/08/07::
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13
Conférence de presse de l
Conférence de presse de l'ALPL et du LCGB-SEA "Lutte contre la fatigue des pilotes (3 octobre 2012)
::2012/10/04::
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14
Alpl + Zufahrt mit Ducati Hypermotard 821
Alpl + Zufahrt mit Ducati Hypermotard 821
::2014/08/28::
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15
ALPL ( Suara si cantik Aira Yudhoyono )
ALPL ( Suara si cantik Aira Yudhoyono )
::2013/12/05::
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16
Harrys liabste Hütt
Harrys liabste Hütt'n Alpl Joglland
::2012/09/19::
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17
Prinzenpaarvorstellung der Faschingsgilde Alpl 2013
Prinzenpaarvorstellung der Faschingsgilde Alpl 2013
::2013/11/07::
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18
Luca Alpl
Luca Alpl'K Part
::2014/03/18::
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19
Schitour aufs Lasaberger Alpl mit Schnikky
Schitour aufs Lasaberger Alpl mit Schnikky
::2012/06/05::
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20
Scheeschuhtouren: Alpl - Stanglalm
Scheeschuhtouren: Alpl - Stanglalm
::2014/02/23::
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21
Gasthof Alpl Hotel - Sirnitz - Austria
Gasthof Alpl Hotel - Sirnitz - Austria
::2014/04/13::
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22
Roseggerhof TV -  Christmettenweg in Peter Rosegger´s Waldheimat - Alpl
Roseggerhof TV - Christmettenweg in Peter Rosegger´s Waldheimat - Alpl
::2009/01/10::
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23
Airtel Lanka | ALPL Logo Launch (Internal Event) by D STUDIO CMB
Airtel Lanka | ALPL Logo Launch (Internal Event) by D STUDIO CMB
::2012/07/06::
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24
17.06.2012 Hagelgewitter Alpl
17.06.2012 Hagelgewitter Alpl
::2012/06/17::
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25
Gasthof Alpl, Sirnitz, Austria
Gasthof Alpl, Sirnitz, Austria
::2014/02/25::
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26
Pilgerweg vom Alpl bis Gh. Postmühle  Teil 3
Pilgerweg vom Alpl bis Gh. Postmühle Teil 3
::2013/07/28::
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27
Pilgerweg vom Alpl is zum Gh. Postmühle Teil 2
Pilgerweg vom Alpl is zum Gh. Postmühle Teil 2
::2013/07/28::
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28
Brechten - Alpl 12.01.2014
Brechten - Alpl 12.01.2014
::2014/01/14::
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29
Nieder Alpl - Seeberg - Pgusch
Nieder Alpl - Seeberg - Pgusch
::2011/07/24::
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30
Schitag Alpl
Schitag Alpl
::2011/02/25::
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31
Peter Roseggers Waldschule in Alpl. Steiermark
Peter Roseggers Waldschule in Alpl. Steiermark
::2008/10/21::
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32
Dolomite Alphorn Concert at Tierser Alpl Alpine Refuge
Dolomite Alphorn Concert at Tierser Alpl Alpine Refuge
::2010/07/29::
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33
Flaurling, jakobs alpl 2
Flaurling, jakobs alpl 2
::2013/01/28::
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34
Tiere am Alpl - Schlagobersbauer
Tiere am Alpl - Schlagobersbauer
::2011/04/24::
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35
Alpl  2011
Alpl 2011
::2011/02/16::
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36
MGF 07.05.2011 Alpl
MGF 07.05.2011 Alpl
::2011/05/07::
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37
James Cottriall Alpl 2011
James Cottriall Alpl 2011
::2011/01/06::
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38
mematvo.at - KW 31 - Jakob der Letzte am Alpl
mematvo.at - KW 31 - Jakob der Letzte am Alpl
::2013/08/06::
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39
Playback Video Vehicle ALPL 6294 date 29th march 14
Playback Video Vehicle ALPL 6294 date 29th march 14
::2014/03/29::
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40
Flaurling, jakobs alpl 4
Flaurling, jakobs alpl 4
::2013/01/28::
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41
Knottenkonzert mit Heidi Pixner beim Tierser Alpl
Knottenkonzert mit Heidi Pixner beim Tierser Alpl
::2011/08/10::
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42
Hofer Alpl
Hofer Alpl
::2012/06/17::
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Wanderung aufs Alpl .-
Wanderung aufs Alpl .-
::2012/11/25::
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44
alpl 2013
alpl 2013
::2013/12/28::
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45
Behind The Scenes at ALPL -- Technical Services
Behind The Scenes at ALPL -- Technical Services
::2009/02/24::
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46
ALPL
ALPL
::2014/04/10::
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47
James Cottriall - Live Almbar in Alpl
James Cottriall - Live Almbar in Alpl
::2013/02/10::
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48
fazer2010 alpl steiermark
fazer2010 alpl steiermark
::2010/10/29::
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Flaurling, jakobs alpl 1
Flaurling, jakobs alpl 1
::2013/01/28::
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Alpl Schikurs 2013
Alpl Schikurs 2013
::2013/01/17::
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RESULTS [51 .. 101]
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Alkaline phosphatase, liver/bone/kidney
Identifiers
Symbols ALPL ; AP-TNAP; APTNAP; HOPS; TNAP; TNSALP
External IDs OMIM171760 MGI87983 HomoloGene37314 ChEMBL: 5979 GeneCards: ALPL Gene
EC number 3.1.3.1
RNA expression pattern
PBB GE ALPL 215783 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 249 11647
Ensembl ENSG00000162551 ENSMUSG00000028766
UniProt P05186 P09242
RefSeq (mRNA) NM_000478 NM_001287172
RefSeq (protein) NP_000469 NP_001274101
Location (UCSC) Chr 1:
21.84 – 21.9 Mb
Chr 4:
137.74 – 137.8 Mb
PubMed search [1] [2]

Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene.[1][2]

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on chromosome 2, whereas the tissue-nonspecific form is located on chromosome 1. The product of this gene is a membrane-bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization. However, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation, since this determines age of onset and severity of symptoms.[3]

References[edit]

  1. ^ Weiss MJ, Henthorn PS, Lafferty MA, Slaughter C, Raducha M, Harris H (Oct 1986). "Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase". Proc Natl Acad Sci U S A 83 (19): 7182–6. doi:10.1073/pnas.83.19.7182. PMC 386679. PMID 3532105. 
  2. ^ Swallow DM, Povey S, Parkar M, Andrews PW, Harris H, Pym B, Goodfellow P (May 1988). "Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1". Ann Hum Genet 50 (Pt 3): 229–35. doi:10.1111/j.1469-1809.1986.tb01043.x. PMID 3446011. 
  3. ^ "Entrez Gene: ALPL alkaline phosphatase, liver/bone/kidney". 

External links[edit]

Further reading[edit]



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