Anti-SSA autoantibodies (also called anti-Ro, or the combination anti-SSA/Ro or anti Ro/SSA autoantibodies) are anti-nuclear autoantibodies that are associated with among many autoimmune diseases, such as systemic lupus erythematosus (SLE), SS/SLE overlap syndrome, subacute cutaneous LE (SCLE), neonatal lupus and primary biliary cirrhosis. Also, they are often present in Sjögren's syndrome. 
Approximately only 0.1 to 0.5 percent of the general population has the antibody.
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