EMD Millipore's LentiBrite™ GFP-Beta Actin Lentiviral Biosensor (Catalogue No. 17-10204)

Channel: EMDMilliporeBiosci   |   2011/09/21
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EMD Millipore
EMD Millipore's LentiBrite™ GFP-Beta Actin Lentiviral Biosensor (Catalogue No. 17-10204)
::2011/09/21::
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Actin filament assembly
Actin filament assembly
::2012/11/26::
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Imaging the Brain While Forming Memories
Imaging the Brain While Forming Memories
::2014/01/23::
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Alex B. actin slo prt. 2
Alex B. actin slo prt. 2
::2010/06/17::
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teci b, vikki b, and diamond b, actin crazy
teci b, vikki b, and diamond b, actin crazy
::2010/06/23::
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Balla-b actin a ass on 45
Balla-b actin a ass on 45
::2011/09/05::
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Tay n B Actin Crazy
Tay n B Actin Crazy
::2008/03/27::
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Shvrkey actin dumb
Shvrkey actin dumb
::2013/11/19::
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Nac b actin ahh fool
Nac b actin ahh fool
::2011/06/01::
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10
max b actin crazy
max b actin crazy
::2009/10/20::
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me and b actin crazy
me and b actin crazy
::2007/06/05::
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WHY R THESE GUYS ACTIN LIKE DEY DNT LIKE FEMALES?
WHY R THESE GUYS ACTIN LIKE DEY DNT LIKE FEMALES?
::2010/05/14::
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The Molecular Basis of Memory: Tracking mRNA in Brain Cells in Real Time
The Molecular Basis of Memory: Tracking mRNA in Brain Cells in Real Time
::2014/01/23::
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14
ME AT ASHLEY HOUSE ACTIN STUPID
ME AT ASHLEY HOUSE ACTIN STUPID
::2007/08/30::
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Actin up
Actin up
::2013/02/28::
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quanda nd whitley b actin crazy
quanda nd whitley b actin crazy
::2010/10/24::
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chucky b actin a fool
chucky b actin a fool
::2009/02/21::
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trigga B actin
trigga B actin' a fool in the whip
::2007/05/02::
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2Live Scrap - Actin Up Ft.TB, JRG & June B - 2Damn Live Part.3
2Live Scrap - Actin Up Ft.TB, JRG & June B - 2Damn Live Part.3
::2013/07/31::
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20
B PHI D ACTIN OUT  AT FROUNT LINE
B PHI D ACTIN OUT AT FROUNT LINE
::2009/12/18::
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GMG TV!!!!! BIG BRUH TRAVY AND B MOORE!!  ACTIN UP
GMG TV!!!!! BIG BRUH TRAVY AND B MOORE!! ACTIN UP
::2010/10/08::
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actin like a ...
actin like a ...
::2008/10/10::
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b phi d actin owt
b phi d actin owt
::2009/06/05::
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Actin Up - Cover Rap
Actin Up - Cover Rap
::2013/07/12::
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ONIE AND JACKIE ACTIN DUMB LOL
ONIE AND JACKIE ACTIN DUMB LOL
::2008/06/24::
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Actin A Fool (A Beat the B Production)
Actin A Fool (A Beat the B Production)
::2007/04/04::
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27
BC Corey Actin up
BC Corey Actin up
::2013/07/26::
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28
me n my friends actin stupid on my b-day
me n my friends actin stupid on my b-day
::2007/11/11::
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29
D_Spen ft.Corry b -we actin up.wmv
D_Spen ft.Corry b -we actin up.wmv
::2010/06/19::
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Actin
Actin
::2014/03/14::
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Freakin
Freakin' Epic-Actin' Up
::2012/11/15::
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Actin a fool wit the frat!
Actin a fool wit the frat!
::2012/04/19::
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chinks- actin up/ goofin lol
chinks- actin up/ goofin lol
::2013/05/07::
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LIL MAN MAN x TURNUPBOII AUBREY x LIL RELL x  ACTIN UP
LIL MAN MAN x TURNUPBOII AUBREY x LIL RELL x ACTIN UP
::2012/12/04::
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35
How a muscle contraction is signalled - Animation
How a muscle contraction is signalled - Animation
::2009/02/04::
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Actin Ah Fool  .
Actin Ah Fool .
::2011/01/26::
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Actin
Actin' Up! (Audio) (Orig. by Asher Roth, Justin Bieber, Rye Rye & Chris Brown)
::2013/07/07::
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Waves of F-actin: Pulse Trains
Waves of F-actin: Pulse Trains
::2013/04/24::
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Kyle Lee - Actin
Kyle Lee - Actin' Bad
::2011/06/06::
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Asher Roth - Actin Up  (feat. Rye Rye, Justin Bieber, & Chris Brown) (2013)
Asher Roth - Actin Up (feat. Rye Rye, Justin Bieber, & Chris Brown) (2013)
::2013/06/26::
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Justin Bieber- Actin Up
Justin Bieber- Actin Up
::2013/06/28::
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1st Class Actin A Fool
1st Class Actin A Fool
::2013/01/03::
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Justin Bieber - Actin Up (Ft. Asher Roth, Chris Brown & Rye Rye)
Justin Bieber - Actin Up (Ft. Asher Roth, Chris Brown & Rye Rye)
::2013/06/25::
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Actin
Actin' up rmx - VokaB ft. Rico Love
::2012/08/15::
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tony actin
tony actin' a fool
::2013/12/16::
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Mom actin like
Mom actin like
::2013/12/03::
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Actin
Actin' By Mr.Lucci
::2010/01/27::
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Scarecrow and Mike P! Sigmas actin foolish!
Scarecrow and Mike P! Sigmas actin foolish!
::2011/01/07::
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AFO 2010 Actin
AFO 2010 Actin' Up With the Power Rangers pt 3
::2010/09/07::
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S&m actin up calvin and nard playin round
S&m actin up calvin and nard playin round
::2013/03/09::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Actin, beta

PDB rendering based on 1atn.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ACTB ; BRWS1; PS1TP5BP1
External IDs OMIM102630 MGI87904 HomoloGene110648 GeneCards: ACTB Gene
RNA expression pattern
PBB GE ACTB 200801 x at tn.png
PBB GE ACTB 213867 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 60 11461
Ensembl ENSG00000075624 ENSMUSG00000029580
UniProt P60709 P60710
RefSeq (mRNA) NM_001101 NM_007393
RefSeq (protein) NP_001092 NP_031419
Location (UCSC) Chr 7:
5.57 – 5.6 Mb
Chr 5:
142.9 – 142.91 Mb
PubMed search [1] [2]

Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins[1] that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.[2]

Interactions[edit]

Beta-actin has been shown to interact with SPTBN2.[3][4] In addition, RNA-binding protein Sam68 was found to interact with the mRNA encoding β-actin, which regulates the synaptic formation of the dendritic spines with its cytoskeletal components.

Clinical relevance[edit]

Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma.[5]

Applications[edit]

Beta actin is usually used as a loading control, for among others, the integrity of cells, protein degradation, in PCR and Western blotting. Its molecular weight is approximately 42 kD.

References[edit]

  1. ^ Hanukoglu I, Tanese N, Fuchs E (February 1983). "Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions". J. Mol. Biol. 163 (4): 673–8. PMID 6842590. 
  2. ^ "Entrez Gene: ACTB actin, beta". 
  3. ^ Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C (May 2001). "LDL-receptor-related protein 6 is a receptor for Dickkopf proteins". Nature 411 (6835): 321–5. doi:10.1038/35077108. PMID 11357136. 
  4. ^ Holleran EA, Ligon LA, Tokito M, Stankewich MC, Morrow JS, Holzbaur EL (September 2001). "beta III spectrin binds to the Arp1 subunit of dynactin". J. Biol. Chem. 276 (39): 36598–605. doi:10.1074/jbc.M104838200. PMID 11461920. 
  5. ^ Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, Cruz-Gordillo P, Knoechel B, Asmann YW, Slager SL, Novak AJ, Dogan A, Ansell SM, Link BK, Zou L, Gould J, Saksena G, Stransky N, Rangel-Escareño C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, Hernández-Lemus E, Schwarz-Cruz y Celis A, Imaz-Rosshandler I, Ojesina AI, Jung J, Pedamallu CS, Lander ES, Habermann TM, Cerhan JR, Shipp MA, Getz G, Golub TR (March 2012). "Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing". Proc. Natl. Acad. Sci. U.S.A. 109 (10): 3879–84. doi:10.1073/pnas.1121343109. PMC 3309757. PMID 22343534. 

Further reading[edit]

See also[edit]

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