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1
Central Chemoreceptors
Central Chemoreceptors
::2013/02/28::
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Peripheral Chemoreceptors
Peripheral Chemoreceptors
::2013/03/02::
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Central and Peripheral Chemoreceptors (CO2 Detection)
Central and Peripheral Chemoreceptors (CO2 Detection)
::2012/06/06::
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03   Breathing control   02   Central chemoreceptors
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::2014/09/23::
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Chemoreceptor Reflex Control of Blood Pressure [HD Animation]
Chemoreceptor Reflex Control of Blood Pressure [HD Animation]
::2014/03/05::
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Altitude Adaptation of Central Chemoreceptors
Altitude Adaptation of Central Chemoreceptors
::2013/12/09::
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Central chemoreceptors (5-2014) by Dr Khaled A Abulfadle
Central chemoreceptors (5-2014) by Dr Khaled A Abulfadle
::2014/05/03::
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Central and Peripheral Chemoreceptors (PART2)
Central and Peripheral Chemoreceptors (PART2)
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03   Breathing control   01   Peripheral chemoreceptors
03 Breathing control 01 Peripheral chemoreceptors
::2014/09/23::
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10
Центральные хеморецепторы
Центральные хеморецепторы
::2014/12/11::
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chemoreceptor control of breathing
chemoreceptor control of breathing
::2014/03/26::
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12
Baroreceptors & Chemoreceptors of Heart
Baroreceptors & Chemoreceptors of Heart
::2013/02/18::
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Shock 14, Neurological compensations in developing shock
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::2013/05/23::
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Peripheral chemoreceptors and regulation of respiration (5-2014) by Dr Khaled A Abulfadle
Peripheral chemoreceptors and regulation of respiration (5-2014) by Dr Khaled A Abulfadle
::2014/05/02::
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15
Cheyne-Stokes Respiration
Cheyne-Stokes Respiration
::2014/09/12::
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The Respiratory Center
The Respiratory Center
::2013/03/02::
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chemoreceptor
chemoreceptor
::2013/02/17::
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chemoreceptors control of breathing
chemoreceptors control of breathing
::2014/03/25::
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Chemoreceptors and copd
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Chemoreceptor Control of Breathing
Chemoreceptor Control of Breathing
::2014/04/11::
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21
Peripheral chemoreceptors (4-2013) by Dr Khaled A Abulfadle
Peripheral chemoreceptors (4-2013) by Dr Khaled A Abulfadle
::2013/04/25::
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Regulation of blood pressure with baroreceptors
Regulation of blood pressure with baroreceptors
::2012/09/12::
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The Respiratory System: Control of Breathing
The Respiratory System: Control of Breathing
::2013/04/17::
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Chemoreceptor Reflex Control of Blood Pressure
Chemoreceptor Reflex Control of Blood Pressure
::2014/06/30::
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How to Pronounce Chemoreceptors
How to Pronounce Chemoreceptors
::2014/01/28::
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Baroreceptor Reflex Control
Baroreceptor Reflex Control
::2012/09/06::
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The Control of Breathing – Part 1
The Control of Breathing – Part 1
::2014/11/05::
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27) Dr.Hani 23/04/2014 [ Ch.6 : nervous regulation of arterial blood pressure]
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::2014/04/24::
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29
Control Of Respiration
Control Of Respiration
::2014/09/08::
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Chemoreceptor Control of Breathing Final Project
Chemoreceptor Control of Breathing Final Project
::2014/03/28::
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Dr.H.Gamal-- Vascular (10) Peripheral Chemoreceptor , ... Intermediate time course regulation.wmv
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Baroreceptors mnemonic
Baroreceptors mnemonic
::2014/01/06::
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Baroreceptor Reflex Control of Blood Pressure [HD Animation]
Baroreceptor Reflex Control of Blood Pressure [HD Animation]
::2014/03/05::
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Sensory_Taste&Smell w- Interpreter
Sensory_Taste&Smell w- Interpreter
::2014/07/02::
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35
How to Pronounce Chemoreception
How to Pronounce Chemoreception
::2014/01/28::
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Part II - Regulation of Blood Pressure (Hormones)
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::2013/05/27::
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a+p 2 lecture on blood vessels cardiovascular -day2 chemoreceptor
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::2013/02/26::
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38
PHYSIOLOGY OF RESPIRATION
PHYSIOLOGY OF RESPIRATION
::2014/05/05::
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Autoregulation - Baroreceptors
Autoregulation - Baroreceptors
::2012/09/10::
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40
Scent Rhythm
Scent Rhythm
::2013/05/15::
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41
Cricket chirping in the forest near the Gela bagpipe festival 2013
Cricket chirping in the forest near the Gela bagpipe festival 2013
::2014/02/27::
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How does taste work?
How does taste work?
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ELSC-ICNC Seminar: Gilad Barnea
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Earthworms / Cacing Tanah
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All About - Earthworm
All About - Earthworm
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End of Chapter 14
End of Chapter 14
::2014/11/04::
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Grand central miami co2 test
Grand central miami co2 test
::2012/11/15::
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48
Sleep
Sleep
::2014/08/03::
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49
An Earthworm walking
An Earthworm walking
::2014/08/15::
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How to Catch Worms for fishing with dish soap in your backyard! How to Fish channel
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RESULTS [51 .. 101]
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Central chemoreceptors of the central nervous system, located on the ventrolateral medullary surface in the vicinity of the exit of the 9th and 10th cranial nerves, are sensitive to the pH of their environment.

These act to detect the changes in pH of nearby cerebral spinal fluid (CSF) that are indicative of altered oxygen or carbon dioxide concentrations available to brain tissues. An increase in carbon dioxide tension of the arteries, often resulting from increased CO2 intake (hypercapnia), indirectly causes the blood to become more acidic; the cerebral spinal fluid pH is closely comparable to plasma, as carbon dioxide easily diffuses across the blood/brain barrier.

However, a change in plasma pH alone will not stimulate central chemoreceptors as H+ are not able to diffuse across the blood–brain barrier into the CSF. Only CO2 levels affect this as it can diffuse across, reacting with H2O to form carbonic acid and thus decrease pH. Central chemoreception remains, in this way, distinct from peripheral chemoreceptors.

The central chemoreception system has also been shown experimentally to respond to hypercapnic hypoxia (elevated CO2, decreased O2) and aqueous sodium cyanide injection into the whole animal [1] and in vitro slice preparation. These methods can be used to mimic some forms of hypoxic hypoxia and they are currently being studied including the detection of variation in arterial CO2 tension acting as a quick-response-system for short term (or emergency) regulation.

This system utilizes a negative feedback system, therefore if the pH of the cerebral spinal fluid does not compare to an ideal “set” level, then the receptor will send an error signal to the effectors and appropriate action may be executed.

Peripheral chemoreceptors (carotid and aortic bodies) and central chemoreceptors (medullary neurons) primarily function to regulate respiratory activity. This is an important mechanism for maintaining arterial blood pO2, pCO2, and pH within appropriate physiological ranges. For example, a fall in arterial pO2 (hypoxemia) or an increase in arterial pCO2 (hypercapnia) leads to an increase in the rate and depth of respiration through activation of the chemoreceptor reflex. Chemoreceptor activity, however, also affects cardiovascular function either directly (by interacting with medullary vasomotor centers) or indirectly (via altered pulmonary stretch receptor activity). Respiratory arrest and circulatory shock (these conditions decrease arterial pO2 and pH, and increase arterial pCO2) dramatically increase chemoreceptor activity leading to enhanced sympathetic outflow to the heart and vasculature via activation of the vasomotor center in the medulla.


See also[edit]

References[edit]

  1. ^ Solomon IC, Edelman NH, Neubauer, JA. Pre-Bötzinger complex functions as a central hypoxia chemosensor for respiration in vivo. J Neurophysiol. 83(5):2854-68, 2000.

External links[edit]

http://www.cvphysiology.com/Blood%20Pressure/BP014.htm


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