HIV-1 Nef Interferes with Host Cell Motility by Deregulation of Cofilin

Channel: cellpressvideo   |   2014/02/10
Play Video
1
HIV-1 Nef Interferes with Host Cell Motility by Deregulation of Cofilin
HIV-1 Nef Interferes with Host Cell Motility by Deregulation of Cofilin
::2014/02/10::
Play Video
2
Activation of ADF(cofilin) mediates attractive growth cone guidance.mov
Activation of ADF(cofilin) mediates attractive growth cone guidance.mov
::2010/06/14::
Play Video
3
biosights: October 31, 2011 - Cofilin severs the ties between cytokinetic nodes
biosights: October 31, 2011 - Cofilin severs the ties between cytokinetic nodes
::2011/10/31::
Play Video
4
regulating actin filament formation
regulating actin filament formation
::2010/11/03::
Play Video
5
Actin filament assembly
Actin filament assembly
::2012/09/05::
Play Video
6
鐵拳歷代 vs VR快打歷代 (大略) - 1 / 3
鐵拳歷代 vs VR快打歷代 (大略) - 1 / 3
::2011/01/22::
Play Video
7
異魔一破關 - 1 / 8
異魔一破關 - 1 / 8
::2011/01/22::
Play Video
8
異魔一破關 - 5 / 8
異魔一破關 - 5 / 8
::2011/01/22::
Play Video
9
異魔一破關 - 8 / 8
異魔一破關 - 8 / 8
::2011/01/22::
Play Video
10
異魔一破關 - 7 / 8
異魔一破關 - 7 / 8
::2011/01/22::
Play Video
11
鐵拳歷代 vs VR快打歷代 (大略) - 3 / 3
鐵拳歷代 vs VR快打歷代 (大略) - 3 / 3
::2011/01/22::
Play Video
12
異魔一破關 - 3 / 8
異魔一破關 - 3 / 8
::2011/01/22::
Play Video
13
異魔一破關 - 6 / 8
異魔一破關 - 6 / 8
::2011/01/22::
Play Video
14
異魔一破關 - 4 / 8
異魔一破關 - 4 / 8
::2011/01/22::
Play Video
15
鐵拳歷代 vs VR快打歷代 (大略) - 2 / 3
鐵拳歷代 vs VR快打歷代 (大略) - 2 / 3
::2011/01/22::
Play Video
16
異魔一破關 - 2 / 8
異魔一破關 - 2 / 8
::2011/01/22::
Play Video
17
魔物獵人三 , 一開始跟村長哈拉
魔物獵人三 , 一開始跟村長哈拉
::2010/12/06::
Play Video
18
[P/3]VR 快打 5 Live 競技場 視頻評測
[P/3]VR 快打 5 Live 競技場 視頻評測
::2011/06/13::
Play Video
19
Opening and Actin-Mediated Resealing of Bacterial Toxin-Induced Transendothelial Cell Tunnels
Opening and Actin-Mediated Resealing of Bacterial Toxin-Induced Transendothelial Cell Tunnels
::2014/02/10::
Play Video
20
Actin depolymerizing factor
Actin depolymerizing factor
::2012/06/22::
Play Video
21
Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures
Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures
::2014/02/10::
Play Video
22
PE1 01 Opening Movie, Day 1-4
PE1 01 Opening Movie, Day 1-4
::2007/03/03::
Play Video
23
電玩宅速配20120518_《VR快打5 最終對決》撈很大 榨乾玩家荷包
電玩宅速配20120518_《VR快打5 最終對決》撈很大 榨乾玩家荷包
::2012/05/18::
Play Video
24
Growth Cones-turning and actin dynamics.m4v
Growth Cones-turning and actin dynamics.m4v
::2011/10/19::
Play Video
25
Parasite EVE 3 stage 3 Hard 實況 01
Parasite EVE 3 stage 3 Hard 實況 01
::2011/12/03::
Play Video
26
HIVAIDSLecture4
HIVAIDSLecture4
::2013/05/18::
Play Video
27
Parasite Eve - New Game - No Damage Speed Run - Day 1·Resonance [Chinese]
Parasite Eve - New Game - No Damage Speed Run - Day 1·Resonance [Chinese]
::2012/03/18::
Play Video
28
異魔_第三次生日OP.wmv
異魔_第三次生日OP.wmv
::2011/02/12::
Play Video
29
電玩宅速配20110826_《VR快打5》最新作移植家用 再現格鬥熱潮
電玩宅速配20110826_《VR快打5》最新作移植家用 再現格鬥熱潮
::2011/08/26::
Play Video
30
The 3rd Birthday (第 3 次生日) - 序章 (1/2)
The 3rd Birthday (第 3 次生日) - 序章 (1/2)
::2011/01/03::
Play Video
31
鐵拳5
鐵拳5
::2006/07/26::
Play Video
32
Live Cell Imaging of Pseudorabies Virus Particles and KIF1A in Neurons
Live Cell Imaging of Pseudorabies Virus Particles and KIF1A in Neurons
::2014/02/11::
Play Video
33
Dynamics of Virus-Induced Stress Granules
Dynamics of Virus-Induced Stress Granules
::2014/02/11::
Play Video
34
Parasite EVE 3 stage 3 Hard 實況 03
Parasite EVE 3 stage 3 Hard 實況 03
::2011/12/03::
Play Video
35
AOU2007鐵拳六宣傳影片
AOU2007鐵拳六宣傳影片
::2007/02/16::
Play Video
36
Plasma Membrane Localization of S. Typhimurium Effectors SspH2 and SseI Requires S-Palmitoylation
Plasma Membrane Localization of S. Typhimurium Effectors SspH2 and SseI Requires S-Palmitoylation
::2014/02/10::
Play Video
37
PS2/NGC VR 快打 e 世代 ~J6 的野心~ - 宣傳影片
PS2/NGC VR 快打 e 世代 ~J6 的野心~ - 宣傳影片
::2009/11/15::
Play Video
38
Virtua Fighter 1 Arcade Version on MODEL1
Virtua Fighter 1 Arcade Version on MODEL1
::2009/05/16::
Play Video
39
Get Screened for HIV.1--Healthy Choices
Get Screened for HIV.1--Healthy Choices
::2011/08/25::
Play Video
40
Parasite EVE 3 stage 3 Hard 實況 05
Parasite EVE 3 stage 3 Hard 實況 05
::2011/12/03::
Play Video
41
Leishmania donovani Reduces miR-122 in Mouse Liver
Leishmania donovani Reduces miR-122 in Mouse Liver
::2014/02/11::
Play Video
42
A Pivotal Role for CXCL12 Signaling in HPV-Mediated Transformation of Keratinocytes
A Pivotal Role for CXCL12 Signaling in HPV-Mediated Transformation of Keratinocytes
::2014/02/10::
Play Video
43
A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy
A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy
::2014/02/10::
Play Video
44
Super-Resolution Dissection of Coordinated Events during Malaria Invasion of Human Erythrocyte
Super-Resolution Dissection of Coordinated Events during Malaria Invasion of Human Erythrocyte
::2014/02/10::
Play Video
45
iNOS affects the metabolic rate of dividing intracellular Leishmania major parasites
iNOS affects the metabolic rate of dividing intracellular Leishmania major parasites
::2014/02/11::
Play Video
46
Host Cell Entry by Apicomplexa Parasites Requires Actin Polymerization in the Host Cell
Host Cell Entry by Apicomplexa Parasites Requires Actin Polymerization in the Host Cell
::2011/01/28::
Play Video
47
Plasmodium Sporozoite Motility Is Modulated by the Turnover of Discrete Adhesion Sites
Plasmodium Sporozoite Motility Is Modulated by the Turnover of Discrete Adhesion Sites
::2014/02/10::
Play Video
48
Street Fighter 4 VR exclusive at Play Expo!
Street Fighter 4 VR exclusive at Play Expo!
::2012/10/31::
Play Video
49
Wound healing cell motility
Wound healing cell motility
::2014/03/17::
Play Video
50
家庭版VR快打.flv
家庭版VR快打.flv
::2011/11/24::
NEXT >>
RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Cofilin 1 (non-muscle)

PDB rendering based on 1q8g.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols CFL1 ; CFL
External IDs OMIM601442 MGI101757 HomoloGene99735 ChEMBL: 1075129 GeneCards: CFL1 Gene
RNA expression pattern
PBB GE CFL1 200021 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1072 12631
Ensembl ENSG00000172757 ENSMUSG00000056201
UniProt P23528 P18760
RefSeq (mRNA) NM_005507 NM_007687
RefSeq (protein) NP_005498 NP_031713
Location (UCSC) Chr 11:
65.59 – 65.63 Mb
Chr 19:
5.49 – 5.49 Mb
PubMed search [1] [2]

Cofilin 1 (non-muscle; n-cofilin), also known as CFL1, is a human gene, part of the ADF/cofilin family.

Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[1]

One group reports that reelin signaling leads to serine3-phosphorylation of cofilin-1, and this interaction may play a role in the reelin-related regulation of neuronal migration.[2][3]

Interactions[edit]

Cofilin 1 has been shown to interact with HSPH1[4] and LIMK1.[5][6]

References[edit]

  1. ^ "Entrez Gene: CFL1 cofilin 1 (non-muscle)". 
  2. ^ Chai X, Förster E, Zhao S, Bock HH, Frotscher M (January 2009). "Reelin stabilizes the actin cytoskeleton of neuronal processes by inducing n-cofilin phosphorylation at serine3". J. Neurosci. 29 (1): 288–99. doi:10.1523/JNEUROSCI.2934-08.2009. PMID 19129405. 
  3. ^ Frotscher M, Chai X, Bock HH, Haas CA, Förster E, Zhao S (April 2009). "Role of Reelin in the development and maintenance of cortical lamination". J Neural Transm 116 (11): 1451–5. doi:10.1007/s00702-009-0228-7. PMID 19396394. 
  4. ^ Saito, Youhei; Doi Kazuya, Yamagishi Nobuyuki, Ishihara Keiichi, Hatayama Takumi (Feb 2004). "Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems". Biochem. Biophys. Res. Commun. (United States) 314 (2): 396–402. doi:10.1016/j.bbrc.2003.12.108. ISSN 0006-291X. PMID 14733918. 
  5. ^ Foletta, Victoria C; Lim Mei Ann, Soosairajah Juliana, Kelly April P, Stanley Edouard G, Shannon Mark, He Wei, Das Supratik, Massague Joan, Bernard Ora, Soosairaiah Juliana (Sep 2003). "Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1". J. Cell Biol. (United States) 162 (6): 1089–98. doi:10.1083/jcb.200212060. ISSN 0021-9525. PMC 2172847. PMID 12963706. 
  6. ^ Maekawa, M; Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S (Aug 1999). "Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase". Science (UNITED STATES) 285 (5429): 895–8. doi:10.1126/science.285.5429.895. ISSN 0036-8075. PMID 10436159. 

Further reading[edit]

Wikipedia content is licensed under the GFDL License

Mashpedia enables any individual or company to promote their own Youtube-hosted videos or Youtube Channels, offering a simple and effective plan to get them in front of our engaged audience.

Want to learn more? Please contact us at: hello@mashpedia.com

Powered by YouTube
LEGAL
  • Mashpedia © 2014