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Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Published: 2017/08/07
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Published: 2016/11/01
Channel: Gene Music Studio
Alport Syndrome - Usmle case based discussion
Alport Syndrome - Usmle case based discussion
Published: 2017/05/29
Channel: Dr.G.Bhanu Prakash
Assembly of Type IV Collagen
Assembly of Type IV Collagen
Published: 2014/06/05
Channel: symmation
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/04
Channel: sparky markett
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL4A2 "COLLAGEN, TYPE IV, ALPHA 2"
Gene Music using Protein Sequence of COL4A2 "COLLAGEN, TYPE IV, ALPHA 2"
Published: 2017/08/07
Channel: Gene Music Studio
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
Published: 2016/02/02
Channel: Revolutionary Lifestyle Design
TRIPLE HELICES OF COLLAGEN
TRIPLE HELICES OF COLLAGEN
Published: 2016/09/11
Channel: Walter Jahn
Professional Supplement Review - Collagen I & III
Professional Supplement Review - Collagen I & III
Published: 2017/02/01
Channel: National Nutrition
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Published: 2012/10/17
Channel: kwhitsitt1
KOREAN Skin Care | NEW Beauty PRODUCTS!
KOREAN Skin Care | NEW Beauty PRODUCTS!
Published: 2017/10/20
Channel: Beauty By Anne-Marie
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Published: 2016/12/10
Channel: Gene Music Studio
ผงเผือกอาร์บูติน + แอคทีฟ แค่ผสมแล้วทาจบทุกปัญหาผิว 😄💓 ซื้อ 3 แถม 1 ตั้งแต่วันนี้ - 30 เมษายน 2560
ผงเผือกอาร์บูติน + แอคทีฟ แค่ผสมแล้วทาจบทุกปัญหาผิว 😄💓 ซื้อ 3 แถม 1 ตั้งแต่วันนี้ - 30 เมษายน 2560
Published: 2017/03/24
Channel: Dernpen Seesa-ard
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/05
Channel: sparky Business
What is the difference between Type 2 and Types 1&3 Collagen?
What is the difference between Type 2 and Types 1&3 Collagen?
Published: 2015/02/13
Channel: NeoCell Collagen
Natural Treatments for Diabetes
Natural Treatments for Diabetes
Published: 2015/07/16
Channel: Dr. Josh Axe
Assembly of Type I Collagen
Assembly of Type I Collagen
Published: 2014/06/05
Channel: symmation
What Is Collagen Triple Helix?
What Is Collagen Triple Helix?
Published: 2017/07/04
Channel: sparky markett
What Is Collagen Type 2 For?
What Is Collagen Type 2 For?
Published: 2017/07/04
Channel: sparky markett
This MIRACLE OIL FIRMS-Plumps-Stimulates Collagen & Deeply Hydrates Skin PLUS GIVEAWAY
This MIRACLE OIL FIRMS-Plumps-Stimulates Collagen & Deeply Hydrates Skin PLUS GIVEAWAY
Published: 2017/09/04
Channel: Clarisa Patterson
Tai Collagen 3
Tai Collagen 3
Published: 2017/09/16
Channel: Sompote Rungraunganekkoon
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Published: 2017/08/07
Channel: Gene Music Studio
mixLabial augmentation using OSTEON™ 3 Collagen
mixLabial augmentation using OSTEON™ 3 Collagen
Published: 2017/08/17
Channel: 치의신보 (데일리덴탈)
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Published: 2013/10/06
Channel: Moof University
Bone Broth Collagen Protein Powder Ancient Nutrition Supplement Review 2017
Bone Broth Collagen Protein Powder Ancient Nutrition Supplement Review 2017
Published: 2017/07/23
Channel: The Gym Rat World
Collagen protein
Collagen protein
Published: 2012/11/04
Channel: Shomu's Biology
Collagen Production - 25HZ, 50HZ, 75HZ, 100HZ with 10HZ
Collagen Production - 25HZ, 50HZ, 75HZ, 100HZ with 10HZ
Published: 2016/04/07
Channel: Anthony Sommer
Become Attractive ~ Beautiful and Irresistible ~ Powerful Beauty Subliminal * Binaural Beats
Become Attractive ~ Beautiful and Irresistible ~ Powerful Beauty Subliminal * Binaural Beats
Published: 2016/12/10
Channel: Immensity Beats
6 Secret Tricks To Grow Your Facial Hair THICKER, FULLER, FASTER | Beard Growth Routine
6 Secret Tricks To Grow Your Facial Hair THICKER, FULLER, FASTER | Beard Growth Routine
Published: 2017/03/22
Channel: alpha m.
Youthing - Anti-Aging / Reverse Aging Process - Binaural Beats
Youthing - Anti-Aging / Reverse Aging Process - Binaural Beats
Published: 2015/07/18
Channel: Magnetic Minds
#04 Biochemistry Protein Primary/Secondary Structure Lecture for Kevin Ahern
#04 Biochemistry Protein Primary/Secondary Structure Lecture for Kevin Ahern's BB 450/550
Published: 2011/10/04
Channel: Kevin Ahern
Look Younger!  Vitamin C - Build Collagen/Remove Dead Skin Cells/Brighten Skin
Look Younger! Vitamin C - Build Collagen/Remove Dead Skin Cells/Brighten Skin
Published: 2017/05/08
Channel: Jenifer Jenkins
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
Published: 2015/09/21
Channel: alpha m.
Be Ceuticals  - Advanced Booster serum - Collagen 3% + Hyaluronic Acid
Be Ceuticals - Advanced Booster serum - Collagen 3% + Hyaluronic Acid
Published: 2017/10/05
Channel: beceuticals
Gene Music using Protein Sequence of COL23A1 "COLLAGEN, TYPE XXIII, ALPHA 1"
Gene Music using Protein Sequence of COL23A1 "COLLAGEN, TYPE XXIII, ALPHA 1"
Published: 2016/10/06
Channel: Gene Music Studio
#5 Biochemistry Lecture (Protein Structure) from Kevin Ahern
#5 Biochemistry Lecture (Protein Structure) from Kevin Ahern's BB 350
Published: 2013/04/09
Channel: Kevin Ahern
Alpha Lipoic Acid: How to Treat the REAL Cause of Type 2 Diabetes
Alpha Lipoic Acid: How to Treat the REAL Cause of Type 2 Diabetes
Published: 2010/12/23
Channel: naturalhealthsherpa
What Is Collagen Type 2 For?
What Is Collagen Type 2 For?
Published: 2017/07/05
Channel: sparky Business
Two Anti-Aging Supplements That Could Change Your Life-Omega 3 Fish Oil & Biotin
Two Anti-Aging Supplements That Could Change Your Life-Omega 3 Fish Oil & Biotin
Published: 2017/04/21
Channel: LittlePoet
Binaural Beats For Life - Perfect Skin Rejuvenation (Pure Tone)
Binaural Beats For Life - Perfect Skin Rejuvenation (Pure Tone)
Published: 2014/11/30
Channel: Binaural Beats For Life
Secondary Structure of Proteins
Secondary Structure of Proteins
Published: 2015/01/29
Channel: AK LECTURES
★ COLLAGEN BOOSTER!★  VERY POWERFUL Anti Aging forumla! Sublimina
★ COLLAGEN BOOSTER!★ VERY POWERFUL Anti Aging forumla! Sublimina
Published: 2016/06/04
Channel: Fabio Siccardi
Alpha-Lipoic Acid - Your Health TV
Alpha-Lipoic Acid - Your Health TV
Published: 2012/01/11
Channel: BIO INNOVATIONS
Make Your Crush Go Crazy Over You - MatrixPlay99
Make Your Crush Go Crazy Over You - MatrixPlay99
Published: 2016/01/13
Channel: MatrixPlay99
ผงเผือกอาร์บูติน ขาวใส ปลอดภัยชัวร์ Alpha Arbutin Collagen
ผงเผือกอาร์บูติน ขาวใส ปลอดภัยชัวร์ Alpha Arbutin Collagen
Published: 2017/07/04
Channel: Nan Nuttaya
Thuốc chống lão hóa Fish Collagen + HA 120 viên của Mỹ có tốt không
Thuốc chống lão hóa Fish Collagen + HA 120 viên của Mỹ có tốt không
Published: 2017/08/12
Channel: VietAir Cargo
Binaural Sleep Music: Alpha brain waves music binaural music for sleep insomnia
Binaural Sleep Music: Alpha brain waves music binaural music for sleep insomnia
Published: 2016/06/25
Channel: NuMeditationMusic
3 Side Seal Sachet VFFS Packing Machine PM-100P for Collagen
3 Side Seal Sachet VFFS Packing Machine PM-100P for Collagen
Published: 2015/08/31
Channel: Alpha-Pack Enterprise Ltd
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WIKIPEDIA ARTICLE

From Wikipedia, the free encyclopedia
  (Redirected from Collagen alpha-3(IV) chain)
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COL4A3
Identifiers
Aliases COL4A3, collagen type IV alpha 3 chain
External IDs MGI: 104688 HomoloGene: 68033 GeneCards: COL4A3
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for COL4A3
Genomic location for COL4A3
Band 2q36.3 Start 227,164,565 bp[1]
End 227,314,792 bp[1]
RNA expression pattern
PBB GE COL4A3 216893 s at fs.png

PBB GE COL4A3 214641 at fs.png

PBB GE COL4A3 222073 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007734

RefSeq (protein)

NP_000082

NP_031760

Location (UCSC) Chr 2: 227.16 – 227.31 Mb Chr 2: 82.59 – 82.72 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene.[5][6]

Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In Goodpasture's syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. There are multiple alternate transcripts that appear to be unique to this human alpha 3 gene and alternate splicing is restricted to the six exons that encode this C-terminal domain. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Some exons of this gene are interspersed with exons of an uncharacterized gene which is on the opposite strand.[6]

Disease Database[edit]

LOVD Alport gene variant databases (COL4A3, COL4A4, COL4A5)

References[edit]

Further reading[edit]


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