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Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Published: 2017/08/07
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Published: 2016/11/01
Channel: Gene Music Studio
Assembly of Type IV Collagen
Assembly of Type IV Collagen
Published: 2014/06/05
Channel: symmation
Alport Syndrome - Usmle case based discussion
Alport Syndrome - Usmle case based discussion
Published: 2017/05/29
Channel: Dr.G.Bhanu Prakash
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/04
Channel: sparky markett
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Published: 2013/10/06
Channel: Moof University
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Published: 2016/12/10
Channel: Gene Music Studio
Assembly of Type I Collagen
Assembly of Type I Collagen
Published: 2014/06/05
Channel: symmation
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
Published: 2016/02/02
Channel: Revolutionary Lifestyle Design
Professional Supplement Review - Collagen I & III
Professional Supplement Review - Collagen I & III
Published: 2017/02/01
Channel: National Nutrition
What is the difference between Type 2 and Types 1&3 Collagen?
What is the difference between Type 2 and Types 1&3 Collagen?
Published: 2015/02/13
Channel: NeoCell Collagen
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
Published: 2015/09/21
Channel: alpha m.
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/05
Channel: sparky Business
Alpha Arbutin 3 plus (viên kích trắng, dưỡng da)
Alpha Arbutin 3 plus (viên kích trắng, dưỡng da)
Published: 2017/10/31
Channel: Aquaselin Chuyên Gia Ngăn tiết mồ hôi & khử mùi
Why YOU Will Age Like SH*T! 10 Reasons You Are Going To Look OLD
Why YOU Will Age Like SH*T! 10 Reasons You Are Going To Look OLD
Published: 2016/12/03
Channel: alpha m.
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Published: 2012/10/17
Channel: kwhitsitt1
What Is Collagen Triple Helix?
What Is Collagen Triple Helix?
Published: 2017/07/04
Channel: sparky markett
What Is Collagen Type 2 For?
What Is Collagen Type 2 For?
Published: 2017/07/04
Channel: sparky markett
ผงเผือกอาร์บูติน ขาวใส ปลอดภัยชัวร์ Alpha Arbutin Collagen
ผงเผือกอาร์บูติน ขาวใส ปลอดภัยชัวร์ Alpha Arbutin Collagen
Published: 2017/07/04
Channel: Nan Nuttaya
How To Look Young And Sexy FOREVER!  6 Secrets To Age Better Than Your Friends
How To Look Young And Sexy FOREVER! 6 Secrets To Age Better Than Your Friends
Published: 2017/02/06
Channel: alpha m.
Tai Collagen 3
Tai Collagen 3
Published: 2017/09/16
Channel: Sompote Rungraunganekkoon
Joe Rogan On Vitamins And Supplements
Joe Rogan On Vitamins And Supplements
Published: 2016/06/03
Channel: Joe Rogan University - Fan Channel
CORRELATION BETWEEN EXPRESSION OF TYPE IV COLLAGEN AND.wmv
CORRELATION BETWEEN EXPRESSION OF TYPE IV COLLAGEN AND.wmv
Published: 2010/07/05
Channel: medicaldtv
Anti-Aging RETINOL! How To Get The MOST Benefits From VITAMIN A! (Look Younger)
Anti-Aging RETINOL! How To Get The MOST Benefits From VITAMIN A! (Look Younger)
Published: 2017/12/02
Channel: Beauty By Anne-Marie
Biochemistry: Protein structure (3)
Biochemistry: Protein structure (3)
Published: 2015/09/22
Channel: freelanceteach
Look Younger!  Vitamin C - Build Collagen/Remove Dead Skin Cells/Brighten Skin
Look Younger! Vitamin C - Build Collagen/Remove Dead Skin Cells/Brighten Skin
Published: 2017/05/08
Channel: Jenifer Jenkins
Alpha helix | Secondary structure of proteins
Alpha helix | Secondary structure of proteins
Published: 2017/04/11
Channel: Shomu's Biology
Biochemistry: Protein structure (4)
Biochemistry: Protein structure (4)
Published: 2015/09/22
Channel: freelanceteach
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Published: 2017/08/07
Channel: Gene Music Studio
Anti Aging mit Collagen - Robert Franz
Anti Aging mit Collagen - Robert Franz
Published: 2017/09/17
Channel: Dawa Ulm
Youthing - Anti-Aging / Reverse Aging Process - Binaural Beats
Youthing - Anti-Aging / Reverse Aging Process - Binaural Beats
Published: 2015/07/18
Channel: Magnetic Minds
Collagen: Intro / Overview - Types of Collagen [free sample]
Collagen: Intro / Overview - Types of Collagen [free sample]
Published: 2017/07/19
Channel: Moof University
ELEMIS Pro-Collagen 3-Piece Hero Collection on QVC
ELEMIS Pro-Collagen 3-Piece Hero Collection on QVC
Published: 2017/10/09
Channel: QVCtv
★ COLLAGEN BOOSTER!★  VERY POWERFUL Anti Aging forumla! Sublimina
★ COLLAGEN BOOSTER!★ VERY POWERFUL Anti Aging forumla! Sublimina
Published: 2016/06/04
Channel: Fabio Siccardi
ผงเผือกอาร์บูติน : สูตรใหม่ขาวไวขึ้น 3 เท่า/ Alpha Arbutin 3Plus
ผงเผือกอาร์บูติน : สูตรใหม่ขาวไวขึ้น 3 เท่า/ Alpha Arbutin 3Plus
Published: 2017/09/11
Channel: Nan Nuttaya
WATSONS• COLLAGEN AND GLUTATHIONE SUPPLEMENT• Pangpa-bata at Pangpa-puti⁉
WATSONS• COLLAGEN AND GLUTATHIONE SUPPLEMENT• Pangpa-bata at Pangpa-puti⁉
Published: 2017/07/14
Channel: Charmie Lagaso
ELEMIS The Power of Pro-Collagen 3-Piece Starter Kit on QVC
ELEMIS The Power of Pro-Collagen 3-Piece Starter Kit on QVC
Published: 2018/01/13
Channel: QVCtv
Alpha Lipoic Acid: How to Treat the REAL Cause of Type 2 Diabetes
Alpha Lipoic Acid: How to Treat the REAL Cause of Type 2 Diabetes
Published: 2010/12/23
Channel: naturalhealthsherpa
Amino acid structures (part 3)
Amino acid structures (part 3)
Published: 2013/08/22
Channel: Shomu's Biology
Top Four Bodybuilding Supplements Worth Your Money @hodgetwins
Top Four Bodybuilding Supplements Worth Your Money @hodgetwins
Published: 2015/11/17
Channel: TwinMuscle
Gene Music using Protein Sequence of COL27A1 "COLLAGEN, TYPE XXVII, ALPHA 1"
Gene Music using Protein Sequence of COL27A1 "COLLAGEN, TYPE XXVII, ALPHA 1"
Published: 2017/08/07
Channel: Gene Music Studio
Collagen
Collagen
Published: 2012/12/01
Channel: Matt Fuchs
3 Best Glutathione in the Philippines na AFFORDABLE | Must TRY!
3 Best Glutathione in the Philippines na AFFORDABLE | Must TRY!
Published: 2017/08/15
Channel: Vanity Room Philippines
What is a Protein? Learn about the 3D shape and function of macromolecules
What is a Protein? Learn about the 3D shape and function of macromolecules
Published: 2013/09/04
Channel: RCSBProteinDataBank
My Top 3 Nootropics (Smart Drugs) For A Peak Performing Brain
My Top 3 Nootropics (Smart Drugs) For A Peak Performing Brain
Published: 2017/08/11
Channel: BulletproofSteven
ELEMIS Pro-Collagen 3-Piece Skincare Kit on QVC
ELEMIS Pro-Collagen 3-Piece Skincare Kit on QVC
Published: 2017/01/14
Channel: QVCtv
Wrinkle Remover Frequency : Collagen Booster & Skin Repair - Anti Aging Delta Binaural Beats #GV83
Wrinkle Remover Frequency : Collagen Booster & Skin Repair - Anti Aging Delta Binaural Beats #GV83
Published: 2017/07/08
Channel: Good Vibes - Binaural Beats
4.  Kevin Ahern
4. Kevin Ahern's Biochemistry - Protein Structure I
Published: 2013/10/08
Channel: Kevin Ahern
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WIKIPEDIA ARTICLE

From Wikipedia, the free encyclopedia
  (Redirected from Collagen alpha-3(IV) chain)
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COL4A3
Identifiers
Aliases COL4A3, collagen type IV alpha 3 chain
External IDs MGI: 104688 HomoloGene: 68033 GeneCards: COL4A3
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for COL4A3
Genomic location for COL4A3
Band 2q36.3 Start 227,164,565 bp[1]
End 227,314,792 bp[1]
RNA expression pattern
PBB GE COL4A3 216893 s at fs.png

PBB GE COL4A3 214641 at fs.png

PBB GE COL4A3 222073 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007734

RefSeq (protein)

NP_000082

NP_031760

Location (UCSC) Chr 2: 227.16 – 227.31 Mb Chr 2: 82.59 – 82.72 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene.[5][6]

Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In Goodpasture's syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. There are multiple alternate transcripts that appear to be unique to this human alpha 3 gene and alternate splicing is restricted to the six exons that encode this C-terminal domain. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Some exons of this gene are interspersed with exons of an uncharacterized gene which is on the opposite strand.[6]

Disease Database[edit]

LOVD Alport gene variant databases (COL4A3, COL4A4, COL4A5)

References[edit]

Further reading[edit]


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