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Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Gene Music using Protein Sequence of COL4A3 "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN)"
Published: 2017/08/07
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Gene Music using Protein Sequence of COL4A3BP "COLLAGEN, TYPE IV, ALPHA 3 (GOODPASTURE ANTIGEN) BIN"
Published: 2016/11/01
Channel: Gene Music Studio
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/04
Channel: sparky markett
Assembly of Type IV Collagen
Assembly of Type IV Collagen
Published: 2014/06/05
Channel: symmation
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Gene Music using Protein Sequence of COL6A3 "COLLAGEN, TYPE VI, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
Gene Music using Protein Sequence of COL4A2 "COLLAGEN, TYPE IV, ALPHA 2"
Gene Music using Protein Sequence of COL4A2 "COLLAGEN, TYPE IV, ALPHA 2"
Published: 2017/08/07
Channel: Gene Music Studio
Joe Rogan On Vitamins And Supplements
Joe Rogan On Vitamins And Supplements
Published: 2016/06/03
Channel: Joe Rogan University - Fan Channel
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Gene Music using Protein Sequence of COL5A3 "COLLAGEN, TYPE V, ALPHA 3"
Published: 2017/08/15
Channel: Gene Music Studio
What Is Collagen Type 3?
What Is Collagen Type 3?
Published: 2017/07/05
Channel: sparky Business
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
How To Fade Acne Scars | Reduce Breakouts | Even Skin Tone At Home |
Published: 2015/09/21
Channel: alpha m.
Professional Supplement Review - Collagen I & III
Professional Supplement Review - Collagen I & III
Published: 2017/02/01
Channel: National Nutrition
The Biggest Fight In Shark Tank History!
The Biggest Fight In Shark Tank History!
Published: 2015/02/22
Channel: Viral Network
What Is Collagen Type 2 For?
What Is Collagen Type 2 For?
Published: 2017/07/05
Channel: sparky Business
What Is Collagen Triple Helix?
What Is Collagen Triple Helix?
Published: 2017/07/04
Channel: sparky markett
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
How To Massively Reduce Joint Pain With Collagen Types 1 & 3
Published: 2016/02/02
Channel: Revolutionary Lifestyle Design
What Is Collagen Type 2 For?
What Is Collagen Type 2 For?
Published: 2017/07/04
Channel: sparky markett
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Gene Music using Protein Sequence of COL9A3 "COLLAGEN, TYPE IX, ALPHA 3"
Published: 2016/12/10
Channel: Gene Music Studio
What Is The Function Of Collagen And Elastin?
What Is The Function Of Collagen And Elastin?
Published: 2017/07/06
Channel: sparky Q
The New Science of AntiAging: Collagen, Hyaluronic Acid & Antioxidants
The New Science of AntiAging: Collagen, Hyaluronic Acid & Antioxidants
Published: 2013/06/09
Channel: NeoCell Collagen
Alport syndrome (mutation in alpha chain of collagen 4)
Alport syndrome (mutation in alpha chain of collagen 4)
Published: 2013/06/05
Channel: USMLEFastTrack
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Gene Music using Protein Sequence of COL4A4 "COLLAGEN, TYPE IV, ALPHA 4"
Published: 2017/08/07
Channel: Gene Music Studio
★ COLLAGEN BOOSTER!★  VERY POWERFUL Anti Aging forumla! Sublimina
★ COLLAGEN BOOSTER!★ VERY POWERFUL Anti Aging forumla! Sublimina
Published: 2016/06/04
Channel: Fabio Siccardi
Gene Music using Protein Sequence of COL27A1 "COLLAGEN, TYPE XXVII, ALPHA 1"
Gene Music using Protein Sequence of COL27A1 "COLLAGEN, TYPE XXVII, ALPHA 1"
Published: 2017/08/07
Channel: Gene Music Studio
Instant Facelift Amazing Results for Younger, Clearer Skin, Subliminal Messages Binaural Beats
Instant Facelift Amazing Results for Younger, Clearer Skin, Subliminal Messages Binaural Beats
Published: 2016/11/19
Channel: Immensity Beats
Why YOU Will Age Like SH*T! 10 Reasons You Are Going To Look OLD
Why YOU Will Age Like SH*T! 10 Reasons You Are Going To Look OLD
Published: 2016/12/03
Channel: alpha m.
How To Look Young And Sexy FOREVER!  6 Secrets To Age Better Than Your Friends
How To Look Young And Sexy FOREVER! 6 Secrets To Age Better Than Your Friends
Published: 2017/02/06
Channel: alpha m.
Look Younger!  Build Collagen/Remove Dead Skin Cells/Brighten Skin
Look Younger! Build Collagen/Remove Dead Skin Cells/Brighten Skin
Published: 2017/05/08
Channel: Jenifer Jenkins
Collagen Booster Frequency : Binaural Beats Hypnosis ★ Wrinkle Remover & Facelift Sound Therapy ★
Collagen Booster Frequency : Binaural Beats Hypnosis ★ Wrinkle Remover & Facelift Sound Therapy ★
Published: 2017/01/31
Channel: Good Vibes - Binaural Beats
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Protein Structure (Part 4 of 4) - Tertiary Structure - Fibrous and Globular Proteins
Published: 2013/10/06
Channel: Moof University
Secondary Structure of Proteins
Secondary Structure of Proteins
Published: 2015/01/29
Channel: AK LECTURES
Collagen Production - 25HZ, 50HZ, 75HZ, 100HZ with 10HZ
Collagen Production - 25HZ, 50HZ, 75HZ, 100HZ with 10HZ
Published: 2016/04/07
Channel: Anthony Sommer
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Alpha Lipoic Acid and Collagen -- How it Helps and Where to Get It!
Published: 2012/10/17
Channel: kwhitsitt1
Gene Music using Protein Sequence of COL3A1 "COLLAGEN, TYPE III, ALPHA 1"
Gene Music using Protein Sequence of COL3A1 "COLLAGEN, TYPE III, ALPHA 1"
Published: 2017/08/07
Channel: Gene Music Studio
WATSONS• COLLAGEN AND GLUTATHIONE SUPPLEMENT• Pangpa-bata at Pangpa-puti⁉
WATSONS• COLLAGEN AND GLUTATHIONE SUPPLEMENT• Pangpa-bata at Pangpa-puti⁉
Published: 2017/07/14
Channel: Charmie Lagaso
Maco Collagen Berkesan dalam 3 HARI
Maco Collagen Berkesan dalam 3 HARI
Published: 2014/12/04
Channel: Maco Collagen Official
PEPTAN BEAUTY Alpha Fish Collagen
PEPTAN BEAUTY Alpha Fish Collagen
Published: 2014/01/20
Channel: chen twu liang jason
What Is The Function Of Collagen And Elastin?
What Is The Function Of Collagen And Elastin?
Published: 2017/07/05
Channel: sparky Business
3 Best Glutathione in the Philippines na AFFORDABLE | Must TRY!
3 Best Glutathione in the Philippines na AFFORDABLE | Must TRY!
Published: 2017/08/15
Channel: Vanity Room Philippines
Concentration Music, Study Music, Relaxing Music for Studying, Soothing Music, Alpha Waves, ☯2820
Concentration Music, Study Music, Relaxing Music for Studying, Soothing Music, Alpha Waves, ☯2820
Published: 2016/06/29
Channel: YellowBrickCinema - Relaxing Music
Natural Treatments for Diabetes
Natural Treatments for Diabetes
Published: 2015/07/16
Channel: Dr. Josh Axe
Thuốc chống lão hóa Fish Collagen + HA 120 viên của Mỹ có tốt không
Thuốc chống lão hóa Fish Collagen + HA 120 viên của Mỹ có tốt không
Published: 2017/08/12
Channel: VietAir Cargo
Viên uống Neocell Collagen Beauty Builder 150 viên của Mỹ có tốt không
Viên uống Neocell Collagen Beauty Builder 150 viên của Mỹ có tốt không
Published: 2017/08/14
Channel: VietAir Cargo
Concentration Music, Study Music, Relaxing Music for Studying, Soothing Music, Alpha Waves, ✿465C
Concentration Music, Study Music, Relaxing Music for Studying, Soothing Music, Alpha Waves, ✿465C
Published: 2015/11/15
Channel: YellowBrickCinema - Relaxing Music
★ Eliminate Wrinkles Quickly! Boost Collagen & Improve Elasticity ★ (Subliminal Frequency Hertz)
★ Eliminate Wrinkles Quickly! Boost Collagen & Improve Elasticity ★ (Subliminal Frequency Hertz)
Published: 2015/04/25
Channel: Quadible Integrity - Subliminal Binaural Beats Meditation Frequency Energy Vibration Intention
OP Marry Collagen เริศสุดใน 3 โลก
OP Marry Collagen เริศสุดใน 3 โลก
Published: 2014/08/03
Channel: ดีเจ. เจ๊กล้วย
Level 1 Tiege Hanley Skin Care System
Level 1 Tiege Hanley Skin Care System
Published: 2017/08/02
Channel: Tiege Hanley
Make Your Crush Go Crazy Over You - MatrixPlay99
Make Your Crush Go Crazy Over You - MatrixPlay99
Published: 2016/01/13
Channel: MatrixPlay99
Hair Growth - Stimulate Hair Growth + Color Restoration - Binaural Beats
Hair Growth - Stimulate Hair Growth + Color Restoration - Binaural Beats
Published: 2015/09/01
Channel: Magnetic Binaurals
Type VII Collagen Expression in the Human Vitreoretinal Interface, Corpora Amylacea and Inner
Type VII Collagen Expression in the Human Vitreoretinal Interface, Corpora Amylacea and Inner
Published: 2015/12/29
Channel: KeSimpulan
Stem Cell Production - II - Anti-Aging, Cure All, Cell, Tissue, Cartilage Regeneration
Stem Cell Production - II - Anti-Aging, Cure All, Cell, Tissue, Cartilage Regeneration
Published: 2016/06/24
Channel: Anthony Sommer
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WIKIPEDIA ARTICLE

From Wikipedia, the free encyclopedia
  (Redirected from Collagen alpha-3(IV) chain)
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COL4A3
Identifiers
Aliases COL4A3, collagen type IV alpha 3 chain
External IDs MGI: 104688 HomoloGene: 68033 GeneCards: COL4A3
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for COL4A3
Genomic location for COL4A3
Band No data available Start 227,164,565 bp[1]
End 227,314,792 bp[1]
RNA expression pattern
PBB GE COL4A3 216893 s at fs.png

PBB GE COL4A3 214641 at fs.png

PBB GE COL4A3 222073 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007734

RefSeq (protein)

NP_000082

NP_031760

Location (UCSC) Chr 2: 227.16 – 227.31 Mb Chr 2: 82.59 – 82.72 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene.[5][6]

Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In Goodpasture's syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. There are multiple alternate transcripts that appear to be unique to this human alpha 3 gene and alternate splicing is restricted to the six exons that encode this C-terminal domain. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Some exons of this gene are interspersed with exons of an uncharacterized gene which is on the opposite strand.[6]

Disease Database[edit]

LOVD Alport gene variant databases (COL4A3, COL4A4, COL4A5)

References[edit]

Further reading[edit]


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