Sorcerer - Rivalry of Balt and Dnai 2
Sorcerer - Rivalry of Balt and Dnai 2
DATE: 2014/10/14::
Sorcerer   review
Sorcerer review
DATE: 2014/10/14::
Go bo nhi dnai1
Go bo nhi dnai1
DATE: 2014/01/11::
Sorcerer - Rivalry of Balt and Dnai 1
Sorcerer - Rivalry of Balt and Dnai 1
DATE: 2014/10/13::
Sorcerer - intro
Sorcerer - intro
DATE: 2014/10/12::
[Thuyết Minh] Ân Tình Bích Huyết Kiếm Tập 15-30
[Thuyết Minh] Ân Tình Bích Huyết Kiếm Tập 15-30
DATE: 2013/01/04::
Sorcerer - Education of Periandrenn
Sorcerer - Education of Periandrenn
DATE: 2014/10/13::
gõ bo nhí lx
gõ bo nhí lx
DATE: 2012/08/04::
RESULTS [9 .. 59]
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Dynein, axonemal, intermediate chain 2
Symbols DNAI2 ; CILD9; DIC2
External IDs OMIM605483 MGI2685574 HomoloGene11311 GeneCards: DNAI2 Gene
Species Human Mouse
Entrez 64446 432611
Ensembl ENSG00000171595 ENSMUSG00000034706
UniProt Q9GZS0 A2AC93
RefSeq (mRNA) NM_001172810 NM_001034878
RefSeq (protein) NP_001166281 NP_001030050
Location (UCSC) Chr 17:
72.27 – 72.31 Mb
Chr 11:
114.73 – 114.76 Mb
PubMed search [1] [2]

Dynein intermediate chain 2, axonemal, also known as axonemal dynein intermediate chain 2, is a protein that in humans is encoded by the DNAI2 gene.[1][2]


The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella.[1]

Clinical significance[edit]

Mutations in the DNAI2 gene are associated with primary ciliary dyskinesia.[3]


  1. ^ a b "Entrez Gene: dynein". 
  2. ^ Pennarun G, Chapelin C, Escudier E, Bridoux AM, Dastot F, Cacheux V, Goossens M, Amselem S, Duriez B (December 2000). "The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia". Hum. Genet. 107 (6): 642–9. doi:10.1007/s004390000427. PMID 11153919. 
  3. ^ Loges NT, Olbrich H, Fenske L, Mussaffi H, Horvath J, Fliegauf M, Kuhl H, Baktai G, Peterffy E, Chodhari R, Chung EM, Rutman A, O'Callaghan C, Blau H, Tiszlavicz L, Voelkel K, Witt M, Zietkiewicz E, Neesen J, Reinhardt R, Mitchison HM, Omran H (November 2008). "DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm". Am. J. Hum. Genet. 83 (5): 547–58. doi:10.1016/j.ajhg.2008.10.001. PMC 2668028. PMID 18950741. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Wikipedia content is licensed under the GFDL License
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