Channel:   |   1970/01/01
RESULTS [1 .. 51]
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Dynein, axonemal, light chain 1
Symbols DNAL1 ; C14orf168; CILD16
External IDs OMIM610062 MGI1921462 HomoloGene34623 GeneCards: DNAL1 Gene
Species Human Mouse
Entrez 83544 105000
Ensembl ENSG00000119661 ENSMUSG00000042523
UniProt Q4LDG9 Q05A62
RefSeq (mRNA) NM_001201366 NM_028821
RefSeq (protein) NP_001188295 NP_083097
Location (UCSC) Chr 14:
74.11 – 74.17 Mb
Chr 12:
84.11 – 84.15 Mb
PubMed search [1] [2]

Dynein light chain 1, axonemal is a protein that in humans is encoded by the DNAL1 gene.[1][2]


DNAL1 is a component of outer dynein arms, which contain the molecular motors for ATP-dependent cilia movement.[1][2]

Clinical significance[edit]

Mutations in the DNAL1 gene are associated with primary ciliary dyskinesia.[3]


  1. ^ a b "Entrez Gene: dynein". 
  2. ^ a b Horváth J, Fliegauf M, Olbrich H, Kispert A, King SM, Mitchison H, Zariwala MA, Knowles MR, Sudbrak R, Fekete G, Neesen J, Reinhardt R, Omran H (July 2005). "Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients". Am. J. Respir. Cell Mol. Biol. 33 (1): 41–7. doi:10.1165/rcmb.2004-0335OC. PMID 15845866. 
  3. ^ Lancaster MA, Gleeson JG (June 2009). "The primary cilium as a cellular signaling center: lessons from disease". Curr. Opin. Genet. Dev. 19 (3): 220–9. doi:10.1016/j.gde.2009.04.008. PMC 2953615. PMID 19477114. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Wikipedia content is licensed under the GFDL License

Mashpedia enables any individual or company to promote their own Youtube-hosted videos or Youtube Channels, offering a simple and effective plan to get them in front of our engaged audience.

Want to learn more? Please contact us at:

Powered by YouTube
  • Mashpedia © 2014