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Dynein, light chain, Tctex-type 1
Identifiers
Symbols DYNLT1 ; CW-1; TCTEL1; tctex-1
External IDs OMIM601554 MGI98643 HomoloGene4754 GeneCards: DYNLT1 Gene
RNA expression pattern
PBB GE DYNLT1 201999 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6993 21648
Ensembl ENSG00000146425 ENSMUSG00000000579
UniProt P63172 P51807
RefSeq (mRNA) NM_001291602 NM_009342
RefSeq (protein) NP_001278531 NP_033368
Location (UCSC) Chr 6:
159.06 – 159.07 Mb
Chr 17:
6.31 – 6.32 Mb
PubMed search [1] [2]

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[1][2][3]

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][3]

References[edit]

  1. ^ Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet 73 (1-2): 153–6. doi:10.1159/000134329. PMID 8646886. 
  2. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502. 
  3. ^ a b "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1". 

Further reading[edit]

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