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Guinness Prime Time - The Werewolf Family.
Guinness Prime Time - The Werewolf Family.
::2012/12/04::
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My Shocking Story - Real Wolf Children
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Hypertrichosis genetics project
Hypertrichosis genetics project
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Hypertrichosis
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DALLAS HAIR TRANSPLANT:  REAL WEREWOLVES AND HYPERTRICHOSIS
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Hypertrichosis with Dr. Janelle Vega Mayoral.wmv
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PSA: Hypertrichosis
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hypertrichosis: the untold true story
hypertrichosis: the untold true story
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hypertrichosis - werewolf - ambras syndrome
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Hypertrichosis Anatomy Vid
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Dermatologist talks about Hypertrichosis on TV
Dermatologist talks about Hypertrichosis on TV
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The World
The World's Hairiest Person and Me | Body Hair | Channel 4
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Interview with Stuart, Hypertrichosis sufferer
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
Jump to: navigation, search
"Werewolf syndrome" redirects here. It is not to be confused with Clinical lycanthropy.
Hypertrichosis
Classification and external resources
ICD-10 L68, Q84.2
ICD-9 704.1, 757.4
OMIM 135400
DiseasesDB 20886
MedlinePlus 003148
eMedicine article/1072031
MeSH D006983
Petrus Gonsalvus, "The Hairy Man" by Joris Hoefnagel from his "Elementa Depicta."

Hypertrichosis (also called Ambras syndrome) is an abnormal amount of hair growth over the body;[1][2] extensive cases of hypertrichosis have informally been called werewolf syndrome,[3] because the appearance is similar to the werewolf. The two distinct types of hypertrichosis are generalized hypertrichosis, which occurs over the entire body, and localized hypertrichosis, which is restricted to a certain area.[1] Hypertrichosis can be either congenital (present at birth) or acquired later in life.[3][4] The excess growth of hair occurs in areas of the skin with the exception of androgen-dependent hair of the pubic area, face, and axillary regions.[5]

Several circus sideshow performers in the 19th and early 20th centuries, such as Julia Pastrana, had hypertrichosis.[6] Many of them worked as freaks and were promoted as having distinct human and animal traits.

Classification[edit]

Two methods of classification are used for hypertrichosis.[4] One divides them into either generalized versus localized hypertrichosis, while the other divides them into congenital versus acquired.[1][7]

Congenital[edit]

Congenital forms of hypertrichosis are caused by genetic mutations, and are extremely rare, unlike acquired forms.[4] Congenital hypertrichosis is always present at birth.[3]

Hypertrichosis lanuginosa

Congenital hypertrichosis lanuginosa is noticeable at birth, with the infant completely covered in thin lanugo hair.[3] In normal circumstances, lanugo hair is shed before birth and replaced by vellus hair; however, in a person with congenital hypertrichosis lanuginosa, the lanugo hair remains after birth.[3] The palms of the hands, soles of the feet, and mucous membranes are not affected.[1] As the person ages, the lanugo hair may thin, leaving only limited areas of hypertrichosis.[8]

Generalized hypertrichosis

Congenital generalized hypertrichosis causes males to exhibit excessive facial and upper body hair, whereas women exhibit less severe asymmetrical hair distribution.[9] The palms, soles, and mucous membranes are not affected.[1]

Terminal hypertrichosis

Congenital terminal hypertrichosis is characterized by the presence of fully pigmented terminal hair that covers the entire body.[3] This condition is usually accompanied by gingival hyperplasia.[3] This form is most responsible for the term "werewolf syndrome" because of the thick, dark hair that appears.[3] People with this condition are sometimes performers at circuses because of their unusual appearance.[3]

Circumscribed hypertrichosis

Congenital circumscribed hypertrichosis is associated with the presence of thick vellus hair on the upper extremities.[10] Circumscribed signifies this type of hypertrichosis is restricted to certain parts of the body, in this case, the extrasensory surfaces of the upper extremities.[10] Hairy elbow syndrome, a type of congenital circumscribed hypertrichosis, shows excessive growth on and around the elbows.[10] This type of hypertrichosis is present at birth, becomes more prominent during aging, and regresses at puberty.[10]

Localized hypertrichosis

Congenital localized hypertrichosis is a localized increase in hair density and length.[4]

Nevoid hypertrichosis

Nevoid hypertrichosis may be present at birth or appear later in life.[3] It features an isolated area of excessive terminal hair and is usually not related to any other diseases.[3][11]

Acquired[edit]

Acquired hypertrichosis appears after birth. The multiple causes include the side effects of drugs, associations with cancer, and possible links with eating disorders. Acquired forms can usually be reduced with various treatments.

Hypertrichosis lanuginosa

Acquired hypertrichosis lanuginosa is characterized by rapid growth of lanugo hair, particularly on the face.[12][13] Hair also appears on the trunk and armpits, while palms and soles are unaffected.[13] The excess hair is commonly referred to as malignant down.[13] This hair is very fine and unpigmented.[13]

Generalized hypertrichosis

Acquired generalized hypertrichosis commonly affects the cheeks, upper lip, and chin.[3][4] This form also affects the forearms and legs, but is less common in these areas. Another deformity associated with acquired generalized hypertrichosis is multiple hairs occupying the same follicle. It may also include abnormal hair growth patterns as what happens to the eyelashes in a condition known as trichiasis.[4] Oral minoxidil treatments for hypertension are known to cause this condition. Topical minoxidil used for alopecia causes hair growth in the areas where it is applied, however this hair disappears shortly after discontinuing the use of topical minoxidil.[14]

Patterned hypertrichosis

Acquired patterned hypertrichosis is an increase in hair growth in a pattern formation. It is similar to acquired generalized hypertrichosis and is a sign of internal malignancy.[5]

Localized hypertrichosis

Acquired localized hypertrichosis is an increase in hair density and length often secondary to irritation or trauma.[15] This form is restricted to certain areas of the body.

Hirsutism[edit]

Main article: Hirsutism

Hypertrichosis is often mistakenly classified as hirsutism.[1] Hirsutism is a type of hypertrichosis exclusive to women and children, resulting from an excess of androgen-sensitive hair growth.[16] Patients with hirsutism exhibit patterns of adult male hair growth.[1] Chest and back hair are often present on women with hirsutism.[16]

Hirsutism is both congenital and acquired. It is linked to excessive male hormones in women, thus symptoms may include acne, deepening of the voice, irregular menstrual periods, and the formation of a more masculine body shape.[16] Increases in androgen (male hormone) levels are the primary cause of most hirsutism cases.[17] If caused by increased levels of androgens, it can be treated with medications that reduce androgen levels. Some birth control pills and spironolactone reduce androgen levels.[16]

Signs and symptoms[edit]

The primary characteristic of all forms of hypertrichosis is excessive hair. Hair in hypertrichosis is usually longer than expected[7] and may consist of any hair type (lanugo, vellus, or terminal).[18] Patterned forms of hypertrichosis cause hair growth in patterns. Generalized forms of hypertrichosis result in hair growth over the entire body. Circumscribed and localized forms lead to hair growth restricted to a certain area.

Differential diagnosis[edit]

Genetic[edit]

X Linked female recessive traits
Patterns of inheritance of females with sex linked forms of hypertrichosis
X Linked male dominant traits
Patterns of inheritance of males with sex linked forms of hypertrichosis
Hypertrichosis lanuginosa

Congenital hypertrichosis lanuginosa may be caused by an inverse mutation on the 8q chromosome;[1] however, it could also be possibly the result of a spontaneous genetic mutation rather than inheritance.[8] This form is a dominant autosomal (not located on the sex chromosomes) cutaneous disorder, that affects the skin.[19]

Generalized hypertrichosis

Congenital generalized hypertrichosis has a dominant pattern of inheritance and has been linked to chromosome x24-q27.1.[1][20] An affected female (carrying the hypertrichosis gene) has a 50% chance of passing it to her offspring. An affected male will pass this form of hypertrichosis to his daughters, but never the sons.

Generalized hypertrichosis terminalis

Congenital generalized hypertrichosis terminalis is thought to be caused by genetic changes on chromosome 17 resulting in the addition or removal of millions of nucleotides.[21] The gene MAP2K6 may be a factor contributing to this condition. This condition may also be due to the change in the chromosome affecting the transcription of genes.[22]

Medical conditions[edit]

Acquired hypertrichosis lanuginosa is commonly present with cancer.[23] This condition is also linked to metabolic disorders, such as anorexia, hormone imbalances, such as hyperthyroidism, or as a side effect of certain drugs.[23]

Acquired generalized hypertrichosis may be caused by cancer. The resulting hair growth is known as malignant down. The mechanism behind cancer induced hypertrichosis is unknown.[3] Oral and topical minoxidil treatments are also known to cause acquired generalized hypertrichosis.[14]

Medications[edit]

Acquired localized hypertrichosis

Minoxidil, a medicine for preventing hair loss, is thought to trigger acquired localized hypertrichosis.[24] Medication-induced hair changes are often reversible.[25]

Other[edit]

Unknown causes

The exact genetic mutation that causes congenital circumscribed, localized, and nevoid hypertrichosis is unknown.[1]

Pathophysiology[edit]

A number of mechanisms can lead to hypertrichosis. One cause involves areas of the skin that are transforming from the small vellus type to the larger terminal type.[7] This change normally occurs during adolescence, when vellus hair follicles in the underarms and groin grow into terminal hair follicles.[1] Hypertrichosis involves this same type of switching, but in areas that do not normally produce terminal hair.[1] The mechanisms for this switch are poorly understood.[1]

Another mechanism involves a change in the hair cycle.[1] There are three stages of the hair cycle: the anagen phase (hair growth), the catagen phase (hair follicle death), and the telogen phase (hair shedding).[1] If the anagen phase increases beyond what is normal; that region of the body will experience excessive hair growth.[7]

Diagnosis[edit]

Hypertrichosis is diagnosed clinically via the occurrence of hair in excess of what is expected for age, sex, and ethnicity in areas that are not androgen-sensitive.[7] The excess can be in the form of excessive length or density and may consist of any hair type (lanugo, vellus, or terminal).[18]

Management[edit]

See also: Hair removal

There is no cure for any congenital forms of hypertrichosis. The treatment for acquired hypertrichosis is based on attempting to address the underlying cause.[18] Acquired forms of hypertrichosis have a variety of sources, and are usually treated by removing the factor causing hypertrichosis, e.g. a medication with undesired side-effects. All hypertrichosis, congenital or acquired, can be reduced through hair removal.[26] Hair removal treatments are categorized into two principal subdivisions: temporary removal and permanent removal.[26] Treatment may have adverse effects by causing scarring, dermatitis, or hypersensitivity.[3]

Temporary hair removal may last from several hours to several weeks, depending on the method used. These procedures are purely cosmetic.[2] Depilation methods, such as trimming, shaving, and depilatories, remove hair to the level of the skin and produce results that last several hours to several days.[27] Epilation methods, such as plucking, electrology, waxing, sugaring, threading remove the entire hair from the root, the results lasting several days to several weeks.[27]

Permanent hair removal uses chemicals, energy of various types, or a combination to target the cells that cause hair growth. Laser hair removal is an effective method of hair removal on hairs that have color. Laser cannot treat white hair. The laser targets the melanin color in the lower 1/3 of the hair follicle, which is the target zone.[2] Electrolysis (electrology) uses electrical current, and/or localized heating. The U.S. Food and Drug Administration (FDA) allows only electrology to use the term "permanent hair removal" because it has been shown to be able treat all colors of hair.

Medication to reduce production of hair is currently under testing. One medicinal option suppresses testosterone by increasing the sex hormone-binding globulin.[28] Another controls the overproduction of hair through the regulation of a luteinizing hormone.[28]

Epidemiology[edit]

Congenital forms of hypertrichosis are rare. Only 50 cases of congenital hypertrichosis lanuginosa have been recorded since the Middle Ages,[3] and fewer than 100 cases of congenital generalized hypertrichosis have been documented in scientific publications and by the media.[22] Congenital generalized hypertrichosis is isolated to one family in Mexico.[1] Acquired hypertrichosis and hirsutism are more common.[4][29] For example, hirsutism occurs in about 10% of women between ages 18 and 45.[29]

Society and culture[edit]

Petrus Gonsalvus (1648), the first recorded case of hypertrichosis[8]

People with hair often found jobs as circus performers, barbers, making the best of their unusual appearance. Fedor Jeftichew ("Jo-Jo the Dog-faced Man"), Stephan Bibrowski ("Lionel the Lion-faced Man"), Jesus "Chuy" Aceves ("Wolfman"), and Annie Jones ("the bearded woman"), all had hypertrichosis.[8] Extensive hypertrichosis carries an emotional burden and can cause cosmetic embarrassment; however, some people attempt no treatments because they say it defines who they are.[2][30]

Julia Pastrana[edit]

Main article: Julia Pastrana

Julia Pastrana (1834–1860)[6] traveled throughout the United States in a freak show as the bearded lady, capturing the attention of many artists.[6] She is portrayed as having dark extensive hairs distributed equally throughout the surface of her body, even on the palms of her hands.[6] Originally, she was believed to have congenital hypertrichosis lanuginosa; however, the generalized form of the syndrome coupled with her gingival hyperlasia indicated that her condition was congenital terminal hypertrichosis.[6][8] This was not confirmed until after her death, when it became clear that her X-linked syndrome resulted in terminal hairs.[8]

Supatra Sasupan[edit]

In 2011, Supattra Sasupan[31] (Thai: สุพัตรา สะสุพันธ์; born August 5, 2000),[31] an 11-year old girl from Thailand with hypertrichosis was named the world's hairiest girl by the Guinness Book of World Records (as Supatra Sasuphan).[32]

The hairy family of Burma[edit]

One record in history concerning congenital hypertrichosis lanuginosa is the hairy family of Burma, a four-generational pedigree of the disease. In 1826, John Crawford was leading a mission for the Governor-General of India through Burma.[33] He tells of meeting a hairy man, Shwe-Maong. Shwe-Maong lived in the court of King Ava and acted as an entertainer.[33] Shwe-Maong had four children: three unaffected children, and one child with congenital hypertrichosis, named Maphoon.[33] On a second mission to Ava, Maphoon was described as a thirty-year-old woman with two sons, one of which had hypertrichosis.[33] The affected son was named Maong-Phoset. He had an affected daughter named Mah-Me.[33] Whereas all affected members of the family had dental problems, the unaffected members had perfect teeth.[33]

History[edit]

The first recorded case of hypertrichosis was Petrus Gonsalvus of the Canary Islands.[8] This was documented by Altrovandus in the late 15th century and published in his text Monstrorum Historia cum Paralipomenis historiae omnium animalium published in 1642.[8][34] He noted two daughters, a son, and a grandchild in Gonzales' family all had hypertrichosis. Altrovandus dubbed them the Ambras family, after the Ambras Castle near Innsbruck, where portraits of the family were found.[8] During the next 300 years, about 50 cases were observed. The scientist Rudolf Virchow described a form of hypertrichosis accompanied by gingival hyperplasia in 1873.[8]

See also[edit]

References[edit]

  1. ^ a b c d e f g h i j k l m n o p Wendelin, D.; Pope, D.; Mallory, S. (2003). "Hypertrichosis". Journal of the American Academy of Dermatology 48 (2): 161–179. doi:10.1067/mjd.2003.100. PMID 12582385. 
  2. ^ a b c d Trüeb, RM (2002). "Causes and management of hypertrichosis". American journal of clinical dermatology 3 (9): 617–27. doi:10.2165/00128071-200203090-00004. PMID 12444804. 
  3. ^ a b c d e f g h i j k l m n o Ngan, Vanessa (June 15, 2009). "Hypertrichosis". DermNet NZ. New Zealand Dermatological Society Incorporated. Retrieved November 29, 2009. 
  4. ^ a b c d e f g Sutton, Richard L. (1916). Diseases of The Skin. St. Louis: C.V. Mosby Company. pp. 408, 705. Retrieved November 29, 2009. 
  5. ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews Diseases of the Skin: Clinical Dermatology (10 ed.). Saunders. p. 769. ISBN 0-7216-2921-0 
  6. ^ a b c d e Miles, A. E. W. (February 1974). "Julia Pastrana: the bearded lady". The Royal Society of Medicine 67 (2): 160–164. PMC 1645262. PMID 4595237. 1645262 
  7. ^ a b c d e Hordinsky, Maria K.; Amy J. McMichael (2008). Hair and Scalp Diseases: Medical, Surgical, and Cosmetic Treatments (Basic and Clinical Dermatology). Informa Healthcare. p. 221. ISBN 1-57444-822-6. 
  8. ^ a b c d e f g h i j Taylor, Sarah K (June 18, 2009). "Congenital Hypertrichosis Lanuginosa". Emedicine. Medscape. Retrieved December 4, 2009. 
  9. ^ Figuera, L.; Pandolfo, M.; Dunne, P.; Cantú, J.; Patel, P. (1995). "Mapping of the congenital generalized hypertrichosis locus to chromosome Xq24-q27.1". Nature Genetics 10 (2): 202–207. doi:10.1038/ng0695-202. PMID 7663516. 
  10. ^ a b c d Escalonilla, P; Aguilar, A; Gallego, M; Piqué, E; Fariña, MC; Requena, L (1996). "A new case of hairy elbows syndrome (Hypertrichosis cubiti)". Pediatric dermatology 13 (4): 303–5. doi:10.1111/j.1525-1470.1996.tb01245.x. PMID 8844750. 
  11. ^ Chang, SN; Hong, CE; Kim, DK; Park, WH (1997). "A case of multiple nevoid hypertrichosis". The Journal of dermatology 24 (5): 337–41. PMID 9198325. 
  12. ^ Samson, Michael K.; Buroker, Thomas R.; Henderson, Michael D.; Baker, Laurence H.; Vaitkevicius, Vainutis K. (2006). "Acquired hypertrichosis lanuginosa". Cancer 36 (4): 1519–1521. doi:10.1002/1097-0142(197510)36:4<1519::AID-CNCR2820360446>3.0.CO;2-H. PMID 1100223. 
  13. ^ a b c d Ngan, Vanessa (June 15, 2009). "Hypertrichosis lanuginosa acquisita". DermNet NZ. New Zealand Dermatological Society Incorporated. Retrieved December 6, 2009. 
  14. ^ a b Gonzales, M.; Landa, N.; Gardeazabal, J.; Calseron, M.J.; Nilbao, I.; Perez, J. L. Diaz (April 27, 2006). "Clinical and Experimental Dermatology". British Association of Dermatologists Journal 19 (2): 157–158. doi:10.1111/j.1365-2230.1994.tb01147.x. 119275626 
  15. ^ Freedberg (2003). Fitzpatrick's Dermatology in General Medicine (6 ed.). McGraw-Hill. p. 651. ISBN 0-07-138076-0. 
  16. ^ a b c d Ehrlich, Steven (August 26, 2008). "Hirsutism". Retrieved December 16, 2009 
  17. ^ Mofid, A.; Seyyed Alinaghi, S. A.; Zandieh, S.; Yazdani, T. (2008). "Hirsutism". International Journal of Clinical Practice 62 (3): 433–43. doi:10.1111/j.1742-1241.2007.01621.x. PMID 18081798. 
  18. ^ a b c Johnson, Richard R.; Wolff, Klaus Dieter (2009). Fitzpatrick's Color Atlas and Synopsis of Clinical Dermatology: Sixth Edition (Fitzpatrick's Color Atlas & Synopsis of Clinical Dermatology). McGraw-Hill Professional. pp. Part 4 Section 32. ISBN 0-07-159975-4. 
  19. ^ Mendiratta, Vibhu; Harjai, Bhawna; Gupta, Tanvi (2008). "Pediatric Dermatology". Pediatric Dermatology (4 ed.) (Lady Hardinge Medical College, Associated Shrimati Sucheta Kriplani and Kalawati Saran Children's Hospital, New Delhi, India: Wiley Periodicals, Inc.) 25 (4): 483–4. doi:10.1111/j.1525-1470.2008.00716.x. PMID 18789097 
  20. ^ Macías-Flores, MA; García-Cruz, D; Rivera, H; Escobar-Luján, M; Melendrez-Vega, A; Rivas-Campos, D; Rodríguez-Collazo, F; Moreno-Arellano, I et al. (1984). "A New Form of Hypertrichosis Inherited as an X-linked Dominant Trait". Human Genetics 66 (1): 66–70. doi:10.1007/BF00275189. PMID 6698556. 
  21. ^ Sun, M.; Li, N.; Dong, W.; Chen, Z.; Liu, Q.; Xu, Y.; He, G.; Shi, Y. et al. (2009). "Copy-Number Mutations on Chromosome 17q24.2-q24.3 in Congenital Generalized Hypertrichosis Terminalis with or without Gingival Hyperplasia". American Journal of Human Genetics 84 (6): 807–813. doi:10.1016/j.ajhg.2009.04.018. PMC 2694973. PMID 19463983. 
  22. ^ a b Ewen Callaway (May 21, 2009). ""Wolf Man" Condition Down To Huge DNA Malfunction". NewScientist. Retrieved November 29, 2009. 
  23. ^ a b Slee, Peter H.Th.J.; Verzijlbergen, Fred J.; Schagen van Leeuwen, Jules H.; van der Waal, Rutger I.F. (2006). "CASE 2. Acquired Hypertrichosis: A Rare Paraneoplastic Syndrome in Various Cancers". Journal of Clinical Oncology 24 (3): 523–524. doi:10.1200/JCO.2005.01.2443. PMID 16421430. 
  24. ^ Earhart, RN; Ball, J; Nuss, DD; Aeling, JL (1977). "Minoxidil-induced hypertrichosis: treatment with calcium thioglycolate depilatory". Southern Medical Journal 70 (4): 442–3. doi:10.1097/00007611-197704000-00023. PMID 850811. 
  25. ^ Piraccini, BM; Iorizzo, M; Rech, G; Tosti, A (2006). "Drug-induced hair disorders". Current drug safety 1 (3): 301–5. doi:10.2174/157488606777934477. PMID 18690941. 
  26. ^ a b Ngan, Vanessa (June 15, 2009). "Hair removal techniques". DermNet NZ. New Zealand Dermatological Society Incorporated. Retrieved November 29, 2009. 
  27. ^ a b Ngan, Vanessa (June 15, 2009). "Epilation". DermNet NZ. New Zealand Dermatological Society Incorporated. Retrieved November 29, 2009. 
  28. ^ a b Clark, Jennifer (October 2006). "Hirsutism May Signal Uderlying Disorder". Dermatology Times 27 (10): 60–61 
  29. ^ a b Mueller, Hans (June 20, 2006). "Definition of Hirsutism". Hirsutism.info. Cirkuit Networks, Inc. Retrieved December 31, 2009. 
  30. ^ John Quinones, Laura Viddy and Cecile Bouchardeau (September 12, 2007). "Hypertrichosis - Real Life Werewolves?". ABC News. Retrieved September 20, 2009. 
  31. ^ a b "วันแรกโกลาหล คอมฯล่ม ทำบัตรประชาชนเด็ก". ข่าวไทยรัฐออนไลน์ (Thai Rath Online). July 12, 2011. Retrieved 2012-07-12.  (Thai) (Supattra Sasupan's Thai national ID card is visible.)
  32. ^ "11-Year-Old 'Delighted' After Being Named World's Hairiest Girl". Fox News. February 28, 2011. Retrieved 2011-03-07. 
  33. ^ a b c d e f Bondeson, J; Miles, A (July 1996). "The hairy family of Burma: a four generation pedigree of congenital hypertrichosis lanuginosa". The Royal Society of Medicine 89 (7): 403–408. PMC 1295857. PMID 8774541. 1295857 
  34. ^ Rashid, Rashid M.; White, Lucile E. (2007). "A hairy development in hypertrichosis: a brief review of Ambras syndrome". Dermatology Online Journal 13 (3): 8. PMID 18328202. 

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