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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Keratin 16
Identifiers
Symbols KRT16 ; CK16; FNEPPK; K16; K1CP; KRT16A; NEPPK
External IDs OMIM148067 MGI96690 HomoloGene21145 GeneCards: KRT16 Gene
Orthologs
Species Human Mouse
Entrez 3868 16666
Ensembl ENSG00000186832 ENSMUSG00000053797
UniProt P08779 Q9Z2K1
RefSeq (mRNA) NM_005557 NM_008470
RefSeq (protein) NP_005548 NP_032496
Location (UCSC) Chr 17:
39.77 – 39.77 Mb
Chr 11:
100.25 – 100.25 Mb
PubMed search [1] [2]

Keratin 16 is a protein that in humans is encoded by the KRT16 gene.[1][2][3]

Keratin 16 is a type I cytokeratin. It is paired with keratin 6 in a number of epithelial tissues, including nail bed, esophagus, tongue, and hair follicles. Mutations in the gene encoding this protein are associated with the genetic skin disorders pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.[4]

External links[edit]

References[edit]

  1. ^ Rosenberg M, RayChaudhury A, Shows TB, Le Beau MM, Fuchs E (February 1988). "A group of type I keratin genes on human chromosome 17: characterization and expression". Mol. Cell. Biol. 8 (2): 722–36. PMC 363198. PMID 2451124. 
  2. ^ Rosenberg M, Fuchs E, Le Beau MM, Eddy RL, Shows TB (1991). "Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12". Cytogenet. Cell Genet. 57 (1): 33–8. doi:10.1159/000133109. PMID 1713141. 
  3. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 
  4. ^ Shamsher MK, Navsaria HA, Stevens HP, Ratnavel RC, Purkis PE, Kelsell DP, McLean WH, Cook LJ, Griffiths WA, Gschmeissner S (October 1995). "Novel mutations in keratin 16 gene underlie focal non-epidermolytic palmoplantar keratoderma (NEPPK) in two families". Hum. Mol. Genet. 4 (10): 1875–81. doi:10.1093/hmg/4.10.1875. PMID 8595410. 

Further reading[edit]

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