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Keratin 17, a diagnostic biomarker for premalignant lesions
Keratin 17, a diagnostic biomarker for premalignant lesions
Published: 2013/06/07
Channel: Stony Brook University
Medical vocabulary: What does Keratin-17 mean
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Channel: WPTV News | West Palm Beach Florida
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Channel: bkeratin
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Brazilian (Permanent) Blow-Dry - Nano Keratin
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Channel: Keratin Research Inc.
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Published: 2015/08/16
Channel: Centro Bellezza
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AMAZON KERATIN - STEP BY STEP tutorial
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Channel: DREAMSFASHION
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Channel: Boys And Girls Hairstyles
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Keratin Hair Extensions | Vivid Hair Review
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ITA - Trattamento lisciante Keratin Plus Gold senza formaldeide - Jean Paul Mynè
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Channel: 角栓の世界 The world of keratin plug
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WIKIPEDIA ARTICLE

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KRT17
Identifiers
Aliases KRT17, K17, PC, PC2, PCHC1, 39.1, CK-17, keratin 17
External IDs OMIM: 148069 MGI: 96691 HomoloGene: 363 GeneCards: KRT17
Gene location (Human)
Chromosome 17 (human)
Chr. Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for KRT17
Genomic location for KRT17
Band 17q21.2 Start 41,619,437 bp[1]
End 41,624,842 bp[1]
RNA expression pattern
PBB GE KRT17 205157 s at fs.png

PBB GE KRT17 212236 x at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000422

NM_010663

RefSeq (protein)

NP_000413

NP_034793

Location (UCSC) Chr 17: 41.62 – 41.62 Mb Chr 17: 100.26 – 100.26 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Keratin, type I cytoskeletal 17 is a protein that in humans is encoded by the KRT17 gene.[5][6][7][8]

Keratin 17 is a type I cytokeratin. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in the gene encoding this protein lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex.[8]

Interactions[edit]

Keratin 17 has been shown to interact with CCDC85B.[9]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128422 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035557 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ McLean WH, Rugg EL, Lunny DP, Morley SM, Lane EB, Swensson O, Dopping-Hepenstal PJ, Griffiths WA, Eady RA, Higgins C (Jul 1995). "Keratin 16 and keratin 17 mutations cause pachyonychia congenita". Nat Genet. 9 (3): 273–8. PMID 7539673. doi:10.1038/ng0395-273. 
  6. ^ Troyanovsky SM, Leube RE, Franke WW (Jan 1993). "Characterization of the human gene encoding cytokeratin 17 and its expression pattern". Eur J Cell Biol. 59 (1): 127–37. PMID 1281771. 
  7. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. PMC 2064177Freely accessible. PMID 16831889. doi:10.1083/jcb.200603161. 
  8. ^ a b "Entrez Gene: KRT17 keratin 17". 
  9. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209. 

Further reading[edit]

External links[edit]


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