| Cyclic lipopeptide antibiotics | |
|---|---|
| Identifiers | |
| TCDB | 1.D.15 |
| OPM superfamily | 172 |
| OPM protein | 1t5n |
A lipopeptide is a molecule consisting of a lipid connected to a peptide. Bacteria express these molecules. They are bound by TLR 1, and other, Toll-like receptors.
Certain lipopeptides are used as antibiotics.[1][2]
Contents |
Examples [edit]
- Surfactin
- Daptomycin
- Echinocandins (e.g., caspofungin)
See also [edit]
References [edit]
- ^ US Patent 6911525 - Lipopeptides as antibacterial agents
- ^ Daptomycin: a lipopeptide antibiotic for the treatment of serious Gram-positive infections , Judith N. Steenbergen*, Jeff Alder, Grace M. Thorne and Francis P. Tally , Journal of Antimicrobial Chemotherapy 2005 55(3):283-288; doi:10.1093/jac/dkh546
Further reading [edit]
- Giuliani A, Pirri G, Nicoletto S (2007). "Antimicrobial peptides: an overview of a promising class of therapeutics". Cent. Eur. J. Biol. 2 (1): 1–33. doi:10.2478/s11535-007-0010-5.
- Pirri G, Giuliani A, Nicoletto S, Pizutto L, Rinaldi A (2009). "Lipopeptides as anti-infectives: a practical perspective". Cent. Eur. J. Biol. 4 (3): 258–273. doi:10.2478/s11535-009-0031-3.
 |
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content is licensed under the GNU Free Document License or Creative Commons CC-BY-SA
Loading...
Top Videos
Latest Videos
Images Source: Flickr. Images licensed under the Creative Commons CC-BY-SA
Here you can share your comments or contribute with more information, content, resources or links about this topic.