House, also known as House, M.D., is an American medical drama series which premiered on Fox on November 16, 2004. House was created by David Shore. The show follows Dr. Gregory House (Hugh Laurie), an irascible, maverick medical genius who heads a team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital (PPTH) in New Jersey. In a typical episode, the team is presented with an unusual case; the storyline follows the diagnosis of the patient's illness, a process often complicated by the internal competition and personal foibles of the diagnostic team. The team leader, House, frequently clashes with his boss (Dr. Lisa Cuddy (Lisa Edelstein)  in seasons 1 through 7, and Dr. Eric Foreman in season 8), and his only friend, Dr. James Wilson (Robert Sean Leonard).