Marc Pingris was born on October 16, 1981 to Jean Marc Pingris, Sr., and Erlinda Prado. Pingris idolized Michael Jordan. After his classes, he would study his lessons and do his homework then go to their barangay court to practice his "Jordan-like" skills in basketball. When he has no classes he would call up his friends and play basketball in other barangays. In high school, Pingris tried to play in their school try-outs but he was not accepted, but when he was in 2nd year he was finally accepted to their school's varsity team. During his collegiate years, he would go play for the varsity basketball team of the Philippine School of Business Administration. However, he started his career at the Far Eastern University, Manila where he was formally discovered.
He was traded to Purefoods after having played a few games with the Express. He was traded along with Egay Billones. In the 2005–06 PBA season, he was awarded with the Finals MVP in the 2006 PBA Philippine Cup as Purefoods defeated Red Bull, 4-2. In Game 2 of the Finals of the 2006 season, he scored 21 points to lead Purefoods to a 93-82 win. In the 2007–08 PBA Philippine Cup Finals, he grabbed a career-high 21 rebounds, leading to his new nickname, The Rebounding Demon.
In a Manila Bulletin interview, Burger King team owner Lito Alvarez further explained the trade: “The reason lang natagalan itong negotiation is we want a draft pick, not a player sa package because we already have 17 players including the three picks we’ll have in this Sunday’s Draft.”
Barely 24 hours after being shipped to Burger King, Pingris was released to the Purefoods TJ Giants after Purefoods agreed to surrender its first and second round picks in 2010 to Burger King.
Pingris' return to Purefoods was confirmed by board governor Rene Pardo in an interview with GMANews.TV: "We have agreed to trade our first and second round picks next year to Burger King for Pingris."
Burger King Whoppers' board representative and then-incoming PBA chairman Lito Alvarez said that he felt that the trade was good for both teams, as Purefoods needed Pingris more, while the Whoppers planned to rebuild with their future draftees.
In the Llamados' second game during the 2012 PBA Commissioner's Cup, Pingris grabbed five rebounds, making him the 42nd member of the league's 1,000 Offensive Rebound Club.
He is married to actress Danica Sotto, daughter of Vic Sotto and Dina Bonnevie. They have two children, a son named Jean Michael, and a daughter named Anielle Micaela.
As shown during his autobiography/documentary series, Kuwentong Gilas, his favorite pastime besides basketball is watching Slam Dunk, and collecting Slam Dunk anime merchandise, especially #10 jersey, worn by his moniker, Hanamichi Sakuragi.