Share

WIKIPEDIA ARTICLE

From Wikipedia, the free encyclopedia
Jump to: navigation, search
+M effect of a methoxy group in an ether
–M effect of a carbonyl group in acrolein

The mesomeric effect in chemistry is a property of substituents or functional groups in a chemical compound. The effect is used in a qualitative way and describes the electron withdrawing or releasing properties of substituents based on relevant resonance structures and is symbolized by the letter M. The mesomeric effect is negative (–M) when the substituent is an electron-withdrawing group and the effect is positive (+M) when the substituent is an electron releasing group.

+M EFFECT ORDER

–O > –NH2 > –NHR > –OR > –NHCOR > –OCOR > –Ph > –F > –Cl > –Br > –I

-M EFFECT ORDER

–NO2 > –CN > --S(=O)2−OH > –CHO > –C=O > –COOCOR > –COOR > –COOH > –CONH2 > –COO

The net electron flow from or to the substituent is determined also by the inductive effect. The mesomeric effect as a result of p-orbital overlap (resonance) has absolutely no effect on this inductive effect, as the inductive effect has purely to do with the electronegativity of the atoms and their topology in the molecule (which atoms are connected to which).

The concepts of mesomeric effect, mesomerism and mesomer were introduced by Ingold in 1938 as an alternative to Pauling's synonymous concept of resonance.[1] "Mesomerism" in this context is often encountered in German and French literature, but in English literature the term "resonance" dominates.

Mesomerism in conjugated systems[edit]

Mesomeric effect can be transmitted along any number of carbon atoms in a conjugated system. This accounts for the resonance stabilization of the molecule due to delocalization of charge. It is important to note that the energy of the actual structure of the molecule, i.e. the resonance hybrid, may be lower than that of any of the contributing resonance structures. The difference in energy between the actual inductive structure and the (most stable contributing structures) worst kinetic structure is called the resonance energy or resonance stabilisation energy. Mesomeric effect is completely different from inductive effect. For the quantitative estimation of the mesomeric/resonance effect strength various substituent constants are used, i.e. Swain-Lupton resonance constant, Taft resonance constant or Oziminski and Dobrowolski pEDA parameter.

See also[edit]

References[edit]

  1. ^ Kerber, Robert C. (2006-02-01). "If It's Resonance, What Is Resonating?". J. Chem. Educ. 83 (2): 223. Bibcode:2006JChEd..83..223K. doi:10.1021/ed083p223. Archived from the original on 2006-10-04. 

External links[edit]

Disclaimer

None of the audio/visual content is hosted on this site. All media is embedded from other sites such as GoogleVideo, Wikipedia, YouTube etc. Therefore, this site has no control over the copyright issues of the streaming media.

All issues concerning copyright violations should be aimed at the sites hosting the material. This site does not host any of the streaming media and the owner has not uploaded any of the material to the video hosting servers. Anyone can find the same content on Google Video or YouTube by themselves.

The owner of this site cannot know which documentaries are in public domain, which has been uploaded to e.g. YouTube by the owner and which has been uploaded without permission. The copyright owner must contact the source if he wants his material off the Internet completely.

Powered by YouTube
Wikipedia content is licensed under the GFDL and (CC) license