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PCDH1
Identifiers
Aliases PCDH1, PC42, PCDH42, protocadherin 1
External IDs MGI: 104692 HomoloGene: 12613 GeneCards: PCDH1
RNA expression pattern
PBB GE PCDH1 215277 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278613
NM_001278615
NM_002587
NM_032420

NM_029357

RefSeq (protein)

NP_001265542
NP_001265544
NP_002578
NP_115796

n/a

Location (UCSC) Chr 5: 141.85 – 141.88 Mb Chr 18: 38.19 – 38.21 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene.[3][4]

This gene belongs to the protocadherin subfamily within the cadherin superfamily. The encoded protein is a membrane protein found at cell-cell boundaries. It is involved in neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity. Alternative splicing occurs in this gene.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Sano K, Tanihara H, Heimark RL, Obata S, Davidson M, St John T, Taketani S, Suzuki S (Jul 1993). "Protocadherins: a large family of cadherin-related molecules in central nervous system". EMBO J. 12 (6): 2249–56. PMC 413453Freely accessible. PMID 8508762. 
  4. ^ a b "Entrez Gene: PCDH1 protocadherin 1". 

Further reading[edit]



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