PFN2

Channel: Tibrus74   |   2013/02/24
Play Video
1
PFN2
PFN2
::2013/02/24::
Play Video
2
2011 05 Torneio Niveis Acro PFN2 EVS Constança Rafaela
2011 05 Torneio Niveis Acro PFN2 EVS Constança Rafaela
::2011/05/29::
Play Video
3
PFN2
PFN2
::2008/02/29::
Play Video
4
Willow Hollow PFN-2
Willow Hollow PFN-2
::2013/09/02::
Play Video
5
"LET
"LET'S GO" - LIVE m/ PFn #2! - (Call of Duty: Ghost)
::2014/03/14::
Play Video
6
PFN 2-4-55 (Lava-Ro)
PFN 2-4-55 (Lava-Ro)
::2012/04/04::
Play Video
7
RN vs PFN 2รอบแล้วนะ PFN
RN vs PFN 2รอบแล้วนะ PFN
::2012/02/07::
Play Video
8
พวกเราคือ PFN 2
พวกเราคือ PFN 2
::2011/11/23::
Play Video
9
PFN 2 ( Primos Felizes News )
PFN 2 ( Primos Felizes News )
::2010/12/09::
Play Video
10
PFN 2
PFN 2
::2010/11/28::
Play Video
11
Salvation Is Here - Ridgefest 2013
Salvation Is Here - Ridgefest 2013
::2013/06/04::
Play Video
12
Cena de Accion de Gracias 2010 - Danzare
Cena de Accion de Gracias 2010 - Danzare
::2011/11/19::
Play Video
13
Akcent - King of Disco (Official Video) (SD).mp4
Akcent - King of Disco (Official Video) (SD).mp4
::2013/11/07::
Play Video
14
Ebo X Gutta- Young Nigga #KlanLyfeMixtape (Shot By. @RaeAccardoSB)
Ebo X Gutta- Young Nigga #KlanLyfeMixtape (Shot By. @RaeAccardoSB)
::2013/07/01::
Play Video
15
Sean being dumb.
Sean being dumb.
::2013/01/01::
Play Video
16
SON OF A CRACKER!(sasha and Mary)
SON OF A CRACKER!(sasha and Mary)
::2009/05/26::
Play Video
17
TG
TG
::2013/03/23::
Play Video
18
Wisin & Yandel   Besos Mojados La Revolucion Official 2009
Wisin & Yandel Besos Mojados La Revolucion Official 2009
::2009/07/03::
Play Video
19
團體 156
團體 156
::2011/01/02::
Play Video
20
Brasada.wmv
Brasada.wmv
::2009/12/29::
Play Video
21
Luncheon of the dead Gameplay (Part 2) Bandicam interupting me...
Luncheon of the dead Gameplay (Part 2) Bandicam interupting me...
::2014/01/20::
Play Video
22
PFN3
PFN3
::2013/02/24::
Play Video
23
Rattlesnake Jake
Rattlesnake Jake's Circus
::2012/01/12::
Play Video
24
Várépítés
Várépítés
::2011/09/18::
Play Video
25
Willow Hollow PFN
Willow Hollow PFN
::2013/09/02::
Play Video
26
3D Buddha
3D Buddha
::2007/08/20::
Play Video
27
MW2: Sick Ts På Rust
MW2: Sick Ts På Rust
::2014/03/15::
Play Video
28
Hiromi en Avenida Q: Mientras más lo amas
Hiromi en Avenida Q: Mientras más lo amas
::2008/06/23::
Play Video
29
Willow Hollow
Willow Hollow
::2013/09/02::
Play Video
30
Ghosts: Beast Cranked gameplay
Ghosts: Beast Cranked gameplay
::2014/03/15::
Play Video
31
Bad lightening lighting
Bad lightening lighting
::2013/09/01::
Play Video
32
Ghosts: That ladder Ts
Ghosts: That ladder Ts
::2014/03/15::
Play Video
33
กิลวอRO13-3-2013 ZIAN [3]
กิลวอRO13-3-2013 ZIAN [3]
::2013/03/13::
Play Video
34
Maquillaje i modelo de primavera
Maquillaje i modelo de primavera
::2014/03/09::
Play Video
35
Ghosts: TS #1
Ghosts: TS #1
::2014/01/02::
Play Video
36
No Claw. #Clean
No Claw. #Clean
::2014/03/20::
Play Video
37
MW2: Epic crane shot
MW2: Epic crane shot
::2014/03/15::
Play Video
38
PFN 6 (Primos Felizes News) HD
PFN 6 (Primos Felizes News) HD
::2011/07/21::
Play Video
39
MW2: Trickshot!
MW2: Trickshot!
::2013/11/05::
Play Video
40
[ทริปเกาะล้าน].wmv
[ทริปเกาะล้าน].wmv
::2012/04/18::
Play Video
41
ESP vs ASC Tournament Skylab-Ro
ESP vs ASC Tournament Skylab-Ro
::2011/12/12::
Play Video
42
Mis cosas de vilu!!!
Mis cosas de vilu!!!
::2014/03/05::
Play Video
43
Pastel de chocolate . Tres minutos en el micro
Pastel de chocolate . Tres minutos en el micro
::2014/03/09::
Play Video
44
PFN vs ORZ Tournament August-Ro Round 5
PFN vs ORZ Tournament August-Ro Round 5
::2011/11/05::
Play Video
45
NMES music class
NMES music class
::2013/11/12::
Play Video
46
PFN vs ORZ Tournament August-Ro (รอบชิงชนะเลิศ)
PFN vs ORZ Tournament August-Ro (รอบชิงชนะเลิศ)
::2011/11/13::
Play Video
47
Ro War Parrying Kill
Ro War Parrying Kill
::2010/01/21::
Play Video
48
MW2: Wallbang!
MW2: Wallbang!
::2013/11/13::
Play Video
49
พวกเรา 2/3
พวกเรา 2/3
::2013/08/30::
Play Video
50
PFN 29-11-55 (Omo-Ro)
PFN 29-11-55 (Omo-Ro)
::2012/11/29::
NEXT >>
RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Profilin 2

PDB rendering based on 1d1j.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols PFN2 ; D3S1319E; PFL
External IDs OMIM176590 MGI97550 HomoloGene130904 GeneCards: PFN2 Gene
RNA expression pattern
PBB GE PFN2 204992 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5217 18645
Ensembl ENSG00000070087 ENSMUSG00000027805
UniProt P35080 Q9JJV2
RefSeq (mRNA) NM_002628 NM_019410.3
RefSeq (protein) NP_002619 NP_062283.1
Location (UCSC) Chr 3:
149.68 – 149.77 Mb
Chr 3:
57.65 – 57.65 Mb
PubMed search [1] [2]

Profilin-2 is a protein that in humans is encoded by the PFN2 gene.[1][2][3]

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.[3]

Interactions[edit]

PFN2 has been shown to interact with ROCK1,[4] Vasodilator-stimulated phosphoprotein,[5][6] CCDC113[7] and FMNL1.[8]

References[edit]

  1. ^ Joensuu T, Blanco G, Pakarinen L, Sistonen P, Kaariainen H, Brown S, Chapelle A, Sankila EM (March 1997). "Refined mapping of the Usher syndrome type III locus on chromosome 3, exclusion of candidate genes, and identification of the putative mouse homologous region". Genomics 38 (3): 255–63. doi:10.1006/geno.1996.0626. PMID 8975700. 
  2. ^ Honore B, Madsen P, Andersen AH, Leffers H (October 1993). "Cloning and expression of a novel human profilin variant, profilin II". FEBS Lett 330 (2): 151–5. doi:10.1016/0014-5793(93)80262-S. PMID 8365484. 
  3. ^ a b "Entrez Gene: PFN2 profilin 2". 
  4. ^ Da Silva, Jorge Santos; Medina Miguel, Zuliani Cecilia, Di Nardo Alessia, Witke Walter, Dotti Carlos G (September 2003). "RhoA/ROCK regulation of neuritogenesis via profilin IIa–mediated control of actin stability". J. Cell Biol. (United States) 162 (7): 1267–79. doi:10.1083/jcb.200304021. ISSN 0021-9525. PMC 2173969. PMID 14517206. 
  5. ^ Reinhard, M; Giehl K, Abel K, Haffner C, Jarchau T, Hoppe V, Jockusch B M, Walter U (April 1995). "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins". EMBO J. (ENGLAND) 14 (8): 1583–9. ISSN 0261-4189. PMC 398250. PMID 7737110. 
  6. ^ Harbeck, B; Hüttelmaier S, Schluter K, Jockusch B M, Illenberger S (October 2000). "Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin". J. Biol. Chem. (UNITED STATES) 275 (40): 30817–25. doi:10.1074/jbc.M005066200. ISSN 0021-9258. PMID 10882740. 
  7. ^ "Coiled-Coil Domain Containing 113". GeneCards. Retrieved 5/8/2013. 
  8. ^ Yayoshi-Yamamoto, S; Taniuchi I, Watanabe T (September 2000). "FRL, a Novel Formin-Related Protein, Binds to Rac and Regulates Cell Motility and Survival of Macrophages". Mol. Cell. Biol. (UNITED STATES) 20 (18): 6872–81. doi:10.1128/MCB.20.18.6872-6881.2000. ISSN 0270-7306. PMC 86228. PMID 10958683. 

Further reading[edit]



Wikipedia content is licensed under the GFDL License

Mashpedia enables any individual or company to promote their own Youtube-hosted videos or Youtube Channels, offering a simple and effective plan to get them in front of our engaged audience.

Want to learn more? Please contact us at: hello@mashpedia.com

Powered by YouTube
LEGAL
  • Mashpedia © 2014