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1
Six1-I.T. corporate film
Six1-I.T. corporate film
::2013/04/17::
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2
Love Crimes of Kabul - Documentary - Afghanistan
Love Crimes of Kabul - Documentary - Afghanistan
::2013/02/15::
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3
Ganna & Nati vs Deerockz / SIX1 CYPHER Battle
Ganna & Nati vs Deerockz / SIX1 CYPHER Battle
::2014/05/11::
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4
I wanna be, "Shata ft Six1" island hop mixtape "KING SQUAD TV"
I wanna be, "Shata ft Six1" island hop mixtape "KING SQUAD TV"
::2013/02/18::
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5
스프릿스礦山six1:22
스프릿스礦山six1:22
::2007/08/01::
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6
스프릿스城鎮手指SIX1:36
스프릿스城鎮手指SIX1:36
::2007/08/01::
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7
D-Boi x Symba - All On Me (prod. Six1) [Thizzler.com Exclusive]
D-Boi x Symba - All On Me (prod. Six1) [Thizzler.com Exclusive]
::2012/08/06::
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8
일여섯 부천!! 씨아이팩토리 인사드립니다. ^^ Six1 unit Network for Bu-Cheon CI-Factory
일여섯 부천!! 씨아이팩토리 인사드립니다. ^^ Six1 unit Network for Bu-Cheon CI-Factory
::2014/06/18::
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9
Ultimate Spiderman Return of the Sinister Six1
Ultimate Spiderman Return of the Sinister Six1
::2015/01/04::
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10
GLOBAL SIX(1) ロト6詐欺師の長い言い訳
GLOBAL SIX(1) ロト6詐欺師の長い言い訳
::2013/05/21::
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11
스프릿스高速公路SIX1:59
스프릿스高速公路SIX1:59
::2007/08/01::
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12
six1
six1
::2015/01/08::
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13
Ultimate Spiderman Return of the Sinister Six1
Ultimate Spiderman Return of the Sinister Six1
::2014/09/30::
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14
Original Rainbow Six 1 (1998). Mission 1: Operation Steel Wind
Original Rainbow Six 1 (1998). Mission 1: Operation Steel Wind
::2011/01/02::
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15
babydoggfree akecimento verbal antes do concerto!!! aniversario guetto six1!!
babydoggfree akecimento verbal antes do concerto!!! aniversario guetto six1!!
::2011/09/11::
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16
스프릿스城鎮公路SIX1:23
스프릿스城鎮公路SIX1:23
::2007/08/01::
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17
RADIO I@SIX1回
RADIO I@SIX1回
::2015/01/22::
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18
스프릿스墓地手指SIX1:34
스프릿스墓地手指SIX1:34
::2007/08/01::
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19
Sonic The Hedgehog Reminiscent Six 1/2
Sonic The Hedgehog Reminiscent Six 1/2
::2013/08/27::
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20
Perry Mason, Silent Six1
Perry Mason, Silent Six1
::2012/03/23::
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21
PC Longplay [154] Tom Clancy
PC Longplay [154] Tom Clancy's Rainbow Six (Part 1 of 2)
::2011/08/26::
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22
스프릿스冰封烈谷SIX1:55
스프릿스冰封烈谷SIX1:55
::2007/08/01::
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23
Rainbow Six1 Ps1 Main Menu Theme
Rainbow Six1 Ps1 Main Menu Theme
::2014/05/04::
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24
12) BIG LIGHTS BIG OL CITY FT Six1 and Krazzy "THE MOVEMENT MIXTAPE" KINGSQUADTV
12) BIG LIGHTS BIG OL CITY FT Six1 and Krazzy "THE MOVEMENT MIXTAPE" KINGSQUADTV
::2013/03/25::
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25
City of Six1
City of Six1
::2012/08/15::
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26
Blue Mountain Summer 2012 - Haloe run on 2009 Norco six1
Blue Mountain Summer 2012 - Haloe run on 2009 Norco six1
::2012/10/16::
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27
Tom Clancy
Tom Clancy's Rainbow Six - Mission 1 Steel Wind
::2010/03/01::
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28
Roderick Six1
Roderick Six1
::2012/12/31::
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29
friends forever-six1
friends forever-six1
::2010/04/14::
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30
sjhong1
sjhong1's ROBLOX video six1
::2014/09/20::
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31
jump val di luce six1 the ssnof
jump val di luce six1 the ssnof
::2007/11/21::
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32
Secret Six #1 REVIEW
Secret Six #1 REVIEW
::2014/12/04::
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Angela Asgard
Angela Asgard's Assassin #1, Secret Six #1, Hulk vs. Thanos #1, more! Unboxing Wednesdays 214
::2014/12/03::
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34
Teenage Mutant Ninja Turtles   S02 E12   The Catwoman From Channel Six1
Teenage Mutant Ninja Turtles S02 E12 The Catwoman From Channel Six1
::2014/09/09::
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35
Marilyn manson "deep six" 1/21/15 md
Marilyn manson "deep six" 1/21/15 md
::2015/01/22::
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36
Secret Six #1 Review What Is The Secret
Secret Six #1 Review What Is The Secret
::2014/12/03::
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37
Six-1 Trick Fix
Six-1 Trick Fix
::2015/01/26::
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38
New 52 SECRET SIX #1 from DC Comics
New 52 SECRET SIX #1 from DC Comics
::2014/12/09::
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39
Apollo & Friends Play Rainbow Six 1 Coop (Part 2)
Apollo & Friends Play Rainbow Six 1 Coop (Part 2)
::2013/06/23::
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40
Rainbow Six 1 (1998) HQ gameplay
Rainbow Six 1 (1998) HQ gameplay
::2011/08/12::
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41
Six 1 Cypher II: The Judges
Six 1 Cypher II: The Judges
::2012/01/03::
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42
Talking Comics for 12.03.14 - Angela #1, Secret Six #1, Thanos Vs Hulk #1, Wolf Moon #1 & More!
Talking Comics for 12.03.14 - Angela #1, Secret Six #1, Thanos Vs Hulk #1, Wolf Moon #1 & More!
::2014/12/01::
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43
Comic Uno Episode 75 (Secret Six #1, Green Arrow #37, and more)
Comic Uno Episode 75 (Secret Six #1, Green Arrow #37, and more)
::2014/12/05::
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44
Comic Review: Secret Six #1
Comic Review: Secret Six #1
::2014/12/12::
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45
KAMATI YA MARIDHIANO SIX  1/4 JUSSA CHUCHU FM 21/SEPT/2014
KAMATI YA MARIDHIANO SIX 1/4 JUSSA CHUCHU FM 21/SEPT/2014
::2014/09/22::
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46
Prison Breaks: Die wahren Geschichten - Die Pittsburgh Six (1/3)
Prison Breaks: Die wahren Geschichten - Die Pittsburgh Six (1/3)
::2010/12/28::
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47
Comic Book Reviews 12/3/14: Blue and Gold, Anarky, Secret Six #1, and MORE!
Comic Book Reviews 12/3/14: Blue and Gold, Anarky, Secret Six #1, and MORE!
::2014/12/03::
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48
Review : Secret Six #1 from DC Comics
Review : Secret Six #1 from DC Comics
::2014/12/08::
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49
El Negro - Massacre [Prod. Six-1] [Thizzler.com]
El Negro - Massacre [Prod. Six-1] [Thizzler.com]
::2013/12/18::
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Secret Six 1
Secret Six 1
::2014/12/04::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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SIX homeobox 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SIX1 ; BOS3; DFNA23; TIP39
External IDs OMIM601205 MGI102780 HomoloGene4360 GeneCards: SIX1 Gene
RNA expression pattern
PBB GE SIX1 205817 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6495 20471
Ensembl ENSG00000126778 ENSMUSG00000051367
UniProt Q15475 Q62231
RefSeq (mRNA) NM_005982 NM_009189
RefSeq (protein) NP_005973 NP_033215
Location (UCSC) Chr 14:
61.11 – 61.12 Mb
Chr 12:
73.04 – 73.05 Mb
PubMed search [1] [2]

Homeobox protein SIX1 is a protein that in humans is encoded by the SIX1 gene.[1][2][3]

The vertebrate SIX genes are homologs of the Drosophila 'sine oculis' (so) gene, which is expressed primarily in the developing visual system of the fly. Members of the SIX gene family encode proteins that are characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. Genes in the SIX family have been shown to play roles in vertebrate and insect development or have been implicated in maintenance of the differentiated state of tissues.[supplied by OMIM][3]

Interactions[edit]

SIX1 has been shown to interact with EYA1[4] and MDFI.[5]

References[edit]

  1. ^ Boucher CA, Carey N, Edwards YH, Siciliano MJ, Johnson KJ (June 1996). "Cloning of the human SIX1 gene and its assignment to chromosome 14". Genomics 33 (1): 140–2. doi:10.1006/geno.1996.0172. PMID 8617500. 
  2. ^ Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM Jr, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F (May 2004). "SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes". Proc Natl Acad Sci U S A 101 (21): 8090–5. doi:10.1073/pnas.0308475101. PMC 419562. PMID 15141091. 
  3. ^ a b "Entrez Gene: SIX1 sine oculis homeobox homolog 1 (Drosophila)". 
  4. ^ Buller, C; Xu X; Marquis V; Schwanke R; Xu P X (November 2001). "Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome". Hum. Mol. Genet. (England) 10 (24): 2775–81. doi:10.1093/hmg/10.24.2775. ISSN 0964-6906. PMID 11734542. 
  5. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]

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