City of Six1

Channel: westtexasjen1   |   2012/08/16
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City of Six1
City of Six1
::2012/08/16::
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Six1
Six1
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six1
six1
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I wanna be, "Shata ft Six1" island hop mixtape "KING SQUAD TV"
I wanna be, "Shata ft Six1" island hop mixtape "KING SQUAD TV"
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Blue Mountain Summer 2012 - Haloe run on 2009 Norco six1
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Six1-I.T. corporate film
Six1-I.T. corporate film
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12) BIG LIGHTS BIG OL CITY FT Six1 and Krazzy "THE MOVEMENT MIXTAPE" KINGSQUADTV
12) BIG LIGHTS BIG OL CITY FT Six1 and Krazzy "THE MOVEMENT MIXTAPE" KINGSQUADTV
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Perry Mason, Silent Six1
Perry Mason, Silent Six1
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Tugun Cannon Ft. Kajun - Pain N Pleasure (prod. by six1)
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스프릿스城鎮手指SIX1:36
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스프릿스礦山six1:22
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2012 12 23 CooCoo SiX1.MOV
2012 12 23 CooCoo SiX1.MOV
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스프릿스城鎮公路SIX1:23
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스프릿스墓地手指SIX1:34
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스프릿스高速公路SIX1:59
스프릿스高速公路SIX1:59
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babydoggfree akecimento verbal antes do concerto!!! aniversario guetto six1!!
babydoggfree akecimento verbal antes do concerto!!! aniversario guetto six1!!
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스프릿스冰封烈谷SIX1:55
스프릿스冰封烈谷SIX1:55
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six1.mpg
six1.mpg
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Love Crimes of Kabul - Documentary - Afghanistan
Love Crimes of Kabul - Documentary - Afghanistan
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tattoo artists history six1
tattoo artists history six1
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Agent six1/2 episode:1 (News Flash)
Agent six1/2 episode:1 (News Flash)
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jump val di luce six1 the ssnof
jump val di luce six1 the ssnof
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Turmfest 2011 SIX1
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tattoo artists get tattooed six1
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friends forever-six1
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KTV "No Fare Onez" Cold Frunt ,Six 1 ,Logic, 2Much,Sagamore , Mr Gremlin, Bangdana, Pete Powerz
KTV "No Fare Onez" Cold Frunt ,Six 1 ,Logic, 2Much,Sagamore , Mr Gremlin, Bangdana, Pete Powerz
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Six1.10.1.2010
Six1.10.1.2010
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Joab Silva "cr7"! Pt.2
Joab Silva "cr7"! Pt.2
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Tom Clancy
Tom Clancy's Rainbow Six - Mission 1 Steel Wind
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Original Rainbow Six 1 (1998). Mission 1: Operation Steel Wind
Original Rainbow Six 1 (1998). Mission 1: Operation Steel Wind
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Original Rainbow Six 1 (1998). Mission 6: Operation Blue Sky
Original Rainbow Six 1 (1998). Mission 6: Operation Blue Sky
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Spider-Man: TAS - S2 E01 - The Insidious Six 1/2 (HD)
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Prison Breaks: Die wahren Geschichten - Die Pittsburgh Six (1/3)
Prison Breaks: Die wahren Geschichten - Die Pittsburgh Six (1/3)
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Cristiano Ronaldo, o jogador mais completo da história do futebol!
Cristiano Ronaldo, o jogador mais completo da história do futebol!
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"Check out how we do " Official video Jah Star  ft Six 1 of KingSquad. KINGSQUAD/THIZZLATIN HONDURAS
"Check out how we do " Official video Jah Star ft Six 1 of KingSquad. KINGSQUAD/THIZZLATIN HONDURAS
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Six 1 Cypher 2 vs 2 Crew battle Jemal & Johanna vs. Dope Roc Kids
Six 1 Cypher 2 vs 2 Crew battle Jemal & Johanna vs. Dope Roc Kids
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Six 1 Cypher II Video 12
Six 1 Cypher II Video 12
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SIX 1 CYPHER III - THE DOCUMENTARY
SIX 1 CYPHER III - THE DOCUMENTARY
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Прохождение - Spider-Man The Sinister Six #1
Прохождение - Spider-Man The Sinister Six #1
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Six 1 Cypher II: The Judges
Six 1 Cypher II: The Judges
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Six 1 Cypher II : Groove Dance Classes
Six 1 Cypher II : Groove Dance Classes
::2012/01/02::
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Rocking out with You Me at Six (1 of 2)
Rocking out with You Me at Six (1 of 2)
::2013/10/15::
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Six 1 Cypher II Video 9 - Me against Santa Claus
Six 1 Cypher II Video 9 - Me against Santa Claus
::2012/01/01::
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Six 1 Cypher II Video 4
Six 1 Cypher II Video 4
::2011/12/29::
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Six 1 Cypher III 2012 - The Judges - Martha (Part 2/3)
Six 1 Cypher III 2012 - The Judges - Martha (Part 2/3)
::2012/05/27::
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GLOBAL SIX(1) ロト6詐欺師の長い言い訳
GLOBAL SIX(1) ロト6詐欺師の長い言い訳
::2013/05/21::
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MT SIX - 1
MT SIX - 1'ones first feat.Karin
::2014/01/30::
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Six 1 Five Apartments - Santa Rosa Apartments For Rent
Six 1 Five Apartments - Santa Rosa Apartments For Rent
::2014/02/13::
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Six 1 Cypher II: Finale
Six 1 Cypher II: Finale
::2012/01/04::
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Revenge of the Sinister Six #1 Rare Comic Book Review
Revenge of the Sinister Six #1 Rare Comic Book Review
::2014/03/20::
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SIX homeobox 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SIX1 ; BOS3; DFNA23; TIP39
External IDs OMIM601205 MGI102780 HomoloGene4360 GeneCards: SIX1 Gene
RNA expression pattern
PBB GE SIX1 205817 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6495 20471
Ensembl ENSG00000126778 ENSMUSG00000051367
UniProt Q15475 Q62231
RefSeq (mRNA) NM_005982 NM_009189
RefSeq (protein) NP_005973 NP_033215
Location (UCSC) Chr 14:
61.11 – 61.12 Mb
Chr 12:
73.04 – 73.05 Mb
PubMed search [1] [2]

Homeobox protein SIX1 is a protein that in humans is encoded by the SIX1 gene.[1][2][3]

The vertebrate SIX genes are homologs of the Drosophila 'sine oculis' (so) gene, which is expressed primarily in the developing visual system of the fly. Members of the SIX gene family encode proteins that are characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. Genes in the SIX family have been shown to play roles in vertebrate and insect development or have been implicated in maintenance of the differentiated state of tissues.[supplied by OMIM][3]

Interactions[edit]

SIX1 has been shown to interact with EYA1[4] and MDFI.[5]

References[edit]

  1. ^ Boucher CA, Carey N, Edwards YH, Siciliano MJ, Johnson KJ (June 1996). "Cloning of the human SIX1 gene and its assignment to chromosome 14". Genomics 33 (1): 140–2. doi:10.1006/geno.1996.0172. PMID 8617500. 
  2. ^ Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM Jr, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F (May 2004). "SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes". Proc Natl Acad Sci U S A 101 (21): 8090–5. doi:10.1073/pnas.0308475101. PMC 419562. PMID 15141091. 
  3. ^ a b "Entrez Gene: SIX1 sine oculis homeobox homolog 1 (Drosophila)". 
  4. ^ Buller, C; Xu X, Marquis V, Schwanke R, Xu P X (November 2001). "Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome". Hum. Mol. Genet. (England) 10 (24): 2775–81. doi:10.1093/hmg/10.24.2775. ISSN 0964-6906. PMID 11734542. 
  5. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]

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