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Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Symbols SLC1A4 ; ASCT1; SATT
External IDs OMIM600229 MGI2135601 HomoloGene20655 IUPHAR: 873 ChEMBL: 2315 GeneCards: SLC1A4 Gene
RNA expression pattern
PBB GE SLC1A4 209610 s at tn.png
PBB GE SLC1A4 209611 s at tn.png
PBB GE SLC1A4 212810 s at tn.png
More reference expression data
Species Human Mouse
Entrez 6509 55963
Ensembl ENSG00000115902 ENSMUSG00000020142
UniProt P43007 O35874
RefSeq (mRNA) NM_001135581 NM_018861
RefSeq (protein) NP_001180422 NP_061349
Location (UCSC) Chr 2:
64.99 – 65.02 Mb
Chr 11:
20.3 – 20.33 Mb
PubMed search [1] [2]

Neutral amino acid transporter A is a protein that in humans is encoded by the SLC1A4 gene.[1][2][3]

In melanocytic cells SLC1A4 gene expression may be regulated by MITF.[4]

See also[edit]


  1. ^ Hofmann K, Duker M, Fink T, Lichter P, Stoffel W (Apr 1995). "Human neutral amino acid transporter ASCT1: structure of the gene (SLC1A4) and localization to chromosome 2p13-p15". Genomics 24 (1): 20–6. doi:10.1006/geno.1994.1577. PMID 7896285. 
  2. ^ Zerangue N, Kavanaugh MP (Dec 1996). "ASCT-1 is a neutral amino acid exchanger with chloride channel activity". J Biol Chem 271 (45): 27991–4. doi:10.1074/jbc.271.45.27991. PMID 8910405. 
  3. ^ "Entrez Gene: SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4". 
  4. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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