The Southern Border Region is one of nine such geopolitical designations in the State of California, USA, used for economic analysis. The region is defined to include San Diego County and Imperial County, each of which borders Mexico. Its largest city is San Diego.
The Southern Border Region is adjacent to the Southern California Region, which consists of five counties. These regions were created in about 1998, when the California Regional Economies Project identified 9 regional economies. The California Economic Strategy Panel uses employment and wage information reported by employers for public policy-making, planning, and program administration. As an example of information reported by the panel, according to the 2009 report, the Gross Domestic Product of the region had grown 68.5% in five years. Other agencies such as the California Public Utilities Commission also provide reports for the region.