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Sunifiram as a Nootropic: a Value Leading Racetam that Delivers Clarity
Sunifiram as a Nootropic: a Value Leading Racetam that Delivers Clarity
Published: 2014/11/03
Channel: Limitless Mindset
(Sunifiram Review) - Ampakine Nootropic
(Sunifiram Review) - Ampakine Nootropic
Published: 2014/01/02
Channel: Jennifer Pauling
Nootropic Review: Sunifiram
Nootropic Review: Sunifiram
Published: 2013/06/26
Channel: Billy Noots
LVUP#28: Sunifiram, Statements/Kommentare [Nootropika, Talk]
LVUP#28: Sunifiram, Statements/Kommentare [Nootropika, Talk]
Published: 2017/06/04
Channel: Zets Base
Nootropics Review. Phenylpiracetam, Bromantane and Sunifiram
Nootropics Review. Phenylpiracetam, Bromantane and Sunifiram
Published: 2017/05/14
Channel: Ushutup Productions
Nootropics on the Unsuspecting
Nootropics on the Unsuspecting
Published: 2013/04/19
Channel: anthonynlee
$4100 in 50 Minutes: The Neurotransmitter Cocktail I Mix to Seduce and Profit
$4100 in 50 Minutes: The Neurotransmitter Cocktail I Mix to Seduce and Profit
Published: 2014/09/15
Channel: Limitless Mindset
Sunifiram - Mandelin Reagent - Normal Test Kit - Bunk Police
Sunifiram - Mandelin Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/08
Channel: Bunk Police
Nootropic Review: Post-exam overview
Nootropic Review: Post-exam overview
Published: 2013/06/22
Channel: Billy Noots
Increase your Concentration & Memory with Oxiracetam by Star Nootropics
Increase your Concentration & Memory with Oxiracetam by Star Nootropics
Published: 2015/06/04
Channel: Steve Cronin
"Smart Drug" Review | Sulbutiamine
"Smart Drug" Review | Sulbutiamine
Published: 2013/08/29
Channel: ThePromisedWLAN
Your Secret Advantage a Nootropic Webinar
Your Secret Advantage a Nootropic Webinar
Published: 2017/03/12
Channel: Eris Fit
Siberian Ginseng the Military Grade Nootropic for Combating Fatigue
Siberian Ginseng the Military Grade Nootropic for Combating Fatigue
Published: 2017/04/10
Channel: Limitless Mindset
Sunifiram - Marquis Reagent - Normal Test Kit - Bunk Police
Sunifiram - Marquis Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/08
Channel: Bunk Police
A Pill That Makes People Learn New Skills as Fast as Children
A Pill That Makes People Learn New Skills as Fast as Children
Published: 2014/04/02
Channel: GeoBeats News
Sunifiram - Hoffman Reagent - Normal Test Kit - Bunk Police
Sunifiram - Hoffman Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/04
Channel: Bunk Police
Sunifiram - Simons Reagent - Normal Test Kit - Bunk Police
Sunifiram - Simons Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/03
Channel: Bunk Police
Noopept as a Nootropic: an Economical Social Smart Drug with Subtle Psychostimulatory Effects
Noopept as a Nootropic: an Economical Social Smart Drug with Subtle Psychostimulatory Effects
Published: 2014/06/02
Channel: Limitless Mindset
Uridine as a Nootropic: the Cofactor that comes from Beer (+Rant)
Uridine as a Nootropic: the Cofactor that comes from Beer (+Rant)
Published: 2015/10/05
Channel: Limitless Mindset
Episode 46 - Improving on Piracetam with Noopept
Episode 46 - Improving on Piracetam with Noopept
Published: 2014/12/20
Channel: Smart Drug Smarts
Methylene Blue Review: The Nootropic drops that make me look like I cannibalized a smurf!
Methylene Blue Review: The Nootropic drops that make me look like I cannibalized a smurf!
Published: 2017/01/16
Channel: Limitless Mindset
Sunifiram - Liebermann Reagent - Normal Test Kit - Bunk Police
Sunifiram - Liebermann Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/08
Channel: Bunk Police
(Phenylpiracetam review) - Racetam Nootropic Benefits
(Phenylpiracetam review) - Racetam Nootropic Benefits
Published: 2014/01/02
Channel: Jennifer Pauling
Nootropics BANNED in the UK!? | This Week in Biohacking EP06
Nootropics BANNED in the UK!? | This Week in Biohacking EP06
Published: 2016/02/15
Channel: Steve Cronin
Phenylpiracetam by LiftMode | 90 Days Later (Review)
Phenylpiracetam by LiftMode | 90 Days Later (Review)
Published: 2014/02/23
Channel: ThePromisedWLAN
Where to buy Sarms
Where to buy Sarms
Published: 2017/03/29
Channel: Cindy Hu
Sunifiram - Robadope Reagent - Normal Test Kit - Bunk Police
Sunifiram - Robadope Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/04
Channel: Bunk Police
Sunifiram - Ehrlich Reagent - Normal Test Kit - Bunk Police
Sunifiram - Ehrlich Reagent - Normal Test Kit - Bunk Police
Published: 2015/12/04
Channel: Bunk Police
2 Nootropics Pre-alcohol + Toxin removal w/ Charcoal
2 Nootropics Pre-alcohol + Toxin removal w/ Charcoal
Published: 2017/07/24
Channel: Cortex Labs Nootropics & Smart Drugs Channel
Sunifiram - Mecke Reagent - Normal Test Kit - Bunk Police
Sunifiram - Mecke Reagent - Normal Test Kit - Bunk Police
Published: 2015/11/11
Channel: Acinad Romanoff
Sunifiram - Froehde Reagent - Normal Test Kit - Bunk Police
Sunifiram - Froehde Reagent - Normal Test Kit - Bunk Police
Published: 2015/11/11
Channel: Acinad Romanoff
Official PRL-8-53 Review/Definitive Breakdown
Official PRL-8-53 Review/Definitive Breakdown
Published: 2017/05/24
Channel: Cortex Labs Nootropics & Smart Drugs Channel
Piracetam Decoded: What +600 Human Studies are Saying about the Enigmatic Smart Drug
Piracetam Decoded: What +600 Human Studies are Saying about the Enigmatic Smart Drug
Published: 2015/03/09
Channel: Limitless Mindset
Why the media gets nootropics DEAD WRONG
Why the media gets nootropics DEAD WRONG
Published: 2017/05/16
Channel: Cortex Labs Nootropics & Smart Drugs Channel
Unifiram · Nootropics
Unifiram · Nootropics
Published: 2015/01/06
Channel: Nootropics TV
LevelUp#1(DE): Nootropika Überblick
LevelUp#1(DE): Nootropika Überblick
Published: 2016/06/12
Channel: Zets Base
Gehirndoping & Vergessen per Pille - Wie Gehirnforschung unser Leben verändert | Let
Gehirndoping & Vergessen per Pille - Wie Gehirnforschung unser Leben verändert | Let's Denk #2
Published: 2012/05/06
Channel: LetsDenk
3 STRONG Reasons for Entrepreneurs to Take Nootropics
3 STRONG Reasons for Entrepreneurs to Take Nootropics
Published: 2017/05/02
Channel: Cortex Labs Nootropics & Smart Drugs Channel
Ампакины
Ампакины
Published: 2016/07/01
Channel: mednauka.net
Biohacking Q&A #4 Tolerance, Cycling strategies, Memantine & Bromantane
Biohacking Q&A #4 Tolerance, Cycling strategies, Memantine & Bromantane
Published: 2017/02/13
Channel: Jonathan Roseland
(Noopept Review) - Benefits & Side Effects
(Noopept Review) - Benefits & Side Effects
Published: 2013/11/29
Channel: Jennifer Pauling
Nootropy (smart drugs, brain boosters). Ziołowe i syntetyczne
Nootropy (smart drugs, brain boosters). Ziołowe i syntetyczne
Published: 2017/06/06
Channel: Pod Mikroskopem
nootropics
nootropics
Published: 2014/04/04
Channel: Peak Nootropics
Car/Desk Smartphone mount for Live streaming- Periscope, Facebook Live
Car/Desk Smartphone mount for Live streaming- Periscope, Facebook Live
Published: 2017/06/06
Channel: Ushutup Productions
LVUP#31.1: OMNIMIND - Was ist drin? Das theoretische Review! [Stack]
LVUP#31.1: OMNIMIND - Was ist drin? Das theoretische Review! [Stack]
Published: 2017/07/30
Channel: Zets Base
(Adrafinil Review) - Benefits & Dangers
(Adrafinil Review) - Benefits & Dangers
Published: 2014/01/02
Channel: Jennifer Pauling
I
I've got Bromantane coming in! - Mechanism + Effect discussion
Published: 2017/05/27
Channel: Cortex Labs Nootropics & Smart Drugs Channel
Welcome to Limitless Mindset (2015)
Welcome to Limitless Mindset (2015)
Published: 2015/02/02
Channel: Limitless Mindset
Vitamin B12 the Vitalizing Nootropic that Sparks Neuroplasticity & Vanquishes Depression
Vitamin B12 the Vitalizing Nootropic that Sparks Neuroplasticity & Vanquishes Depression
Published: 2014/12/08
Channel: Limitless Mindset
Coluracetam Review
Coluracetam Review
Published: 2017/06/30
Channel: brotropics
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WIKIPEDIA ARTICLE

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Sunifiram
Sunifiram.svg
Legal status
Legal status
  • US: Not FDA approved; unscheduled
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C14H18N2O2
Molar mass 246.304 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Sunifiram (DM-235) is a piperazine derived research chemical which has anti-amnesiac effects in animal studies with significantly higher potency than piracetam.[1] Sunifiram is a molecular simplification of unifiram.[2] Based on in vitro and animal studies, it appears that sunifiram acts via AMPA-receptor activation.[3]

As of 2016, sunifiram had not been subjected to toxicology testing, nor to any human clinical trials, and is not approved for use anywhere in the world.[1]

References[edit]

  1. ^ a b Gualtieri F (2016). "Unifi nootropics from the lab to the web: a story of academic (and industrial) shortcomings". Journal of Enzyme Inhibition and Medicinal Chemistry. 31 (2): 187–94. PMID 25831025. doi:10.3109/14756366.2015.1021252. 
  2. ^ Manetti, D.; Ghelardini, C.; Bartolini, A.; Dei, S.; Galeotti, N.; Gualtieri, F.; Romanelli, M. N.; Teodori, E. (2000). "Molecular simplification of 1,4-diazabicyclo4.3.0nonan-9-ones gives piperazine derivatives that maintain high nootropic activity". Journal of Medicinal Chemistry. 43 (23): 4499–4507. PMID 11087574. doi:10.1021/jm000972h. 
  3. ^ Galeotti, N.; Ghelardini, C.; Pittaluga, A.; Pugliese, A.; Bartolini, A.; Manetti, D.; Romanelli, M.; Gualtieri, F. (2003). "AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram)". Naunyn-Schmiedeberg's archives of pharmacology. 368 (6): 538–545. PMID 14600801. doi:10.1007/s00210-003-0812-6. 

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