Play Video
1
WereAllTrue TPM1
WereAllTrue TPM1
::2014/06/24::
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2
WereAllTrue TPM1
WereAllTrue TPM1
::2014/06/24::
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3
WEREALLTRUE TPM1
WEREALLTRUE TPM1
::2014/06/28::
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4
WereAllTrue TPM1 Response - RazR Neon
WereAllTrue TPM1 Response - RazR Neon
::2014/06/18::
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5
TPM1 - PERFUME PNEUMATIC CRIMPING HEAD - semi auto glass bottle crimping machine perfume crimping
TPM1 - PERFUME PNEUMATIC CRIMPING HEAD - semi auto glass bottle crimping machine perfume crimping
::2012/05/23::
Play Video
6
TPM1 pneumatic crimping head
TPM1 pneumatic crimping head
::2013/07/18::
Play Video
7
Werealltrue TPM1
Werealltrue TPM1
::2014/07/06::
Play Video
8
WereAllTrue Private Match Challenge #TPM1
WereAllTrue Private Match Challenge #TPM1
::2014/06/24::
Play Video
9
TPM1
TPM1
::2007/11/26::
Play Video
10
putih abu abu smk n 3 oku 2012 (tpm1) part 2.wmv
putih abu abu smk n 3 oku 2012 (tpm1) part 2.wmv
::2012/05/20::
Play Video
11
Amispoppia-Call On Me (TPM1 Remix) *Party Hard* ᴴᴰ
Amispoppia-Call On Me (TPM1 Remix) *Party Hard* ᴴᴰ
::2013/05/12::
Play Video
12
PUTIH  abu abu smk n 3 oku 2012 (tpm1) part 3.wmv
PUTIH abu abu smk n 3 oku 2012 (tpm1) part 3.wmv
::2012/05/20::
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13
tpm1.MOV
tpm1.MOV
::2010/04/02::
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14
Geng Motor TPm1 Smk N 1 Gempol
Geng Motor TPm1 Smk N 1 Gempol
::2012/06/21::
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15
Rsbi tpm1 menggila1
Rsbi tpm1 menggila1
::2012/01/27::
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16
TPM1
TPM1
::2013/07/23::
Play Video
17
putih abu abu smk n 3 oku 2012 (tpm1).wmv
putih abu abu smk n 3 oku 2012 (tpm1).wmv
::2012/05/20::
Play Video
18
TPM1(SMK NEGERI 3 OKU).wmv
TPM1(SMK NEGERI 3 OKU).wmv
::2011/04/25::
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19
Maísa Martins tpm1
Maísa Martins tpm1
::2011/06/01::
Play Video
20
BPPKT TPM1 Harlem Shake
BPPKT TPM1 Harlem Shake
::2013/05/31::
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21
TPM1.avi
TPM1.avi
::2012/02/17::
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22
saat gila tpm1 baturaja
saat gila tpm1 baturaja
::2013/01/27::
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23
AREG " TPM1
AREG " TPM1
::2013/06/01::
Play Video
24
TPM1
TPM1
::2012/04/28::
Play Video
25
Motor Touring TPm1 smkn 1 Gempol
Motor Touring TPm1 smkn 1 Gempol
::2012/06/21::
Play Video
26
X Tpm1 Syuper Soccer.3gp
X Tpm1 Syuper Soccer.3gp
::2012/05/13::
Play Video
27
tpm1.mov
tpm1.mov
::2010/06/04::
Play Video
28
TPM1
TPM1
::2010/10/29::
Play Video
29
Test kratkog spoja TPM1-2KLP.avi
Test kratkog spoja TPM1-2KLP.avi
::2011/11/20::
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30
SagaTPM - Episódio 1 - Malditas maçãs!
SagaTPM - Episódio 1 - Malditas maçãs!
::2012/02/18::
Play Video
31
TPM 1
TPM 1
::2009/09/13::
Play Video
32
★ Let
★ Let's Design AutoCAD Mechanical #1 - Extrudedichtung [HD] Part 1
::2013/12/21::
Play Video
33
KR4 Midseason Report
KR4 Midseason Report
::2013/08/18::
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34
Fourth of July in Seaworld
Fourth of July in Seaworld
::2013/07/05::
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35
virada de ano (2012)MONTE  SIÃO DE CARAPINA
virada de ano (2012)MONTE SIÃO DE CARAPINA
::2012/01/02::
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36
Aulas de dança com LILIAN & CAMILA !   Alunas   ALDACI & IRENE
Aulas de dança com LILIAN & CAMILA ! Alunas ALDACI & IRENE
::2009/11/14::
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37
WereAllTrue Challenge shot response
WereAllTrue Challenge shot response
::2014/07/11::
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38
Chamblon2012_jnicolet_course1_et_essai2
Chamblon2012_jnicolet_course1_et_essai2
::2012/06/21::
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39
1708164223
1708164223
::2013/08/17::
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40
310674
310674
::2012/07/19::
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41
b2b 26300
b2b 26300
::2008/09/06::
Play Video
42
★ Let
★ Let's Design AutoCAD Mechanical #2 - Extrudedichtung [HD] Part 2
::2013/12/21::
Play Video
43
TPM2 Full
TPM2 Full
::2013/12/22::
Play Video
44
COMO DESCARGAR MUSICA DE YOUTUBE 2013
COMO DESCARGAR MUSICA DE YOUTUBE 2013
::2013/01/01::
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45
Phone Rings Goodbye (long edit) by Brenton Duvall
Phone Rings Goodbye (long edit) by Brenton Duvall
::2012/12/07::
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46
Palukka sejati
Palukka sejati
::2013/05/31::
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47
PANASONIC CF 19 FOR SALE
PANASONIC CF 19 FOR SALE
::2010/10/03::
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48
Pego de surpresa
Pego de surpresa
::2010/11/01::
Play Video
49
XII TKJ 002
XII TKJ 002
::2012/03/02::
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50
Blits Jowo
Blits Jowo
::2012/06/21::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Tropomyosin 1 (alpha)
Protein TPM1 PDB 1c1g.png
PDB rendering based on 1c1g.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TPM1 ; C15orf13; CMD1Y; CMH3; HTM-alpha; TMSA
External IDs OMIM191010 MGI98809 HomoloGene128484 GeneCards: TPM1 Gene
RNA expression pattern
PBB GE TPM1 210986 s at tn.png
PBB GE TPM1 206116 s at tn.png
PBB GE TPM1 210987 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7168 22003
Ensembl ENSG00000140416 ENSMUSG00000032366
UniProt P09493 Q545Y3
RefSeq (mRNA) NM_000366 NM_024427
RefSeq (protein) NP_000357 NP_077745
Location (UCSC) Chr 15:
63.33 – 63.36 Mb
Chr 9:
66.82 – 66.85 Mb
PubMed search [1] [2]

Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene.[1]

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.[2]

Interactions[edit]

TPM1 has been shown to interact with TPM2.[3]

References[edit]

  1. ^ Mogensen J, Kruse TA, Borglum AD (Jun 1999). "Refined localization of the human alpha-tropomyosin gene (TPM1) by genetic mapping". Cytogenet Cell Genet 84 (1-2): 35–6. doi:10.1159/000015207. PMID 10343096. 
  2. ^ "Entrez Gene: TPM1 tropomyosin 1 (alpha)". 
  3. ^ Brown, H R; Schachat F H (Apr 1985). "Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 82 (8): 2359–63. doi:10.1073/pnas.82.8.2359. ISSN 0027-8424. PMC 397557. PMID 3857586. 

Further reading[edit]

External links[edit]


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