Play Video
1
Amispoppia-Call On Me (TPM1 Remix) *Party Hard* ᴴᴰ
Amispoppia-Call On Me (TPM1 Remix) *Party Hard* ᴴᴰ
::2013/05/12::
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2
TPM1 - PERFUME PNEUMATIC CRIMPING HEAD - semi auto glass bottle crimping machine perfume crimping
TPM1 - PERFUME PNEUMATIC CRIMPING HEAD - semi auto glass bottle crimping machine perfume crimping
::2012/05/23::
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3
TPM1
TPM1
::2007/11/26::
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4
putih abu abu smk n 3 oku 2012 (tpm1) part 2.wmv
putih abu abu smk n 3 oku 2012 (tpm1) part 2.wmv
::2012/05/20::
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5
TPM1 pneumatic crimping head
TPM1 pneumatic crimping head
::2013/07/18::
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6
TPM1
TPM1
::2007/06/28::
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7
TPM1
TPM1
::2013/07/23::
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8
PUTIH  abu abu smk n 3 oku 2012 (tpm1) part 3.wmv
PUTIH abu abu smk n 3 oku 2012 (tpm1) part 3.wmv
::2012/05/21::
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9
TPM1
TPM1
::2012/04/28::
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10
Geng Motor TPm1 Smk N 1 Gempol
Geng Motor TPm1 Smk N 1 Gempol
::2012/06/21::
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11
Motor Touring TPm1 smkn 1 Gempol
Motor Touring TPm1 smkn 1 Gempol
::2012/06/21::
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12
TPM1(SMK NEGERI 3 OKU).wmv
TPM1(SMK NEGERI 3 OKU).wmv
::2011/04/25::
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13
tpm1.mov
tpm1.mov
::2010/06/04::
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14
Rsbi tpm1 menggila1
Rsbi tpm1 menggila1
::2012/01/27::
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15
tpm1.MOV
tpm1.MOV
::2010/04/02::
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16
saat gila tpm1 baturaja
saat gila tpm1 baturaja
::2013/01/27::
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17
Maísa Martins tpm1
Maísa Martins tpm1
::2011/06/02::
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18
BPPKT TPM1 Harlem Shake
BPPKT TPM1 Harlem Shake
::2013/05/31::
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19
AREG " TPM1
AREG " TPM1
::2013/06/01::
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20
putih abu abu smk n 3 oku 2012 (tpm1).wmv
putih abu abu smk n 3 oku 2012 (tpm1).wmv
::2012/05/20::
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21
TPM1
TPM1
::2010/10/29::
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22
X Tpm1 Syuper Soccer.3gp
X Tpm1 Syuper Soccer.3gp
::2012/05/13::
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23
TPM1.avi
TPM1.avi
::2012/02/18::
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24
Test kratkog spoja TPM1-2KLP.avi
Test kratkog spoja TPM1-2KLP.avi
::2011/11/20::
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25
SagaTPM - Episódio 1 - Malditas maçãs!
SagaTPM - Episódio 1 - Malditas maçãs!
::2012/02/18::
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26
TPM #1 O que vc faria se eu morresse?
TPM #1 O que vc faria se eu morresse?
::2014/02/26::
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27
Luciana By Night: Luciana questiona a existência da famosa TPM (1)
Luciana By Night: Luciana questiona a existência da famosa TPM (1)
::2013/12/13::
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28
Disque dur interne HDD Seagate Barracuda 7200.14 TPM 1 To modèle ST1000DM003 - Version OEM
Disque dur interne HDD Seagate Barracuda 7200.14 TPM 1 To modèle ST1000DM003 - Version OEM
::2014/02/24::
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29
DE TUDO UM POUCO - Como lidar com a TPM? 1/2
DE TUDO UM POUCO - Como lidar com a TPM? 1/2
::2013/11/14::
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30
DONA TPM 1 - Analista
DONA TPM 1 - Analista
::2013/12/22::
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31
TPM 1 Tích phân mặt loại 1- 20121030 00354
TPM 1 Tích phân mặt loại 1- 20121030 00354
::2012/10/31::
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32
Kl tpm(1)
Kl tpm(1)
::2013/02/07::
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33
COD na TPM #1: Rage everywhere
COD na TPM #1: Rage everywhere
::2014/03/21::
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34
Battlefield 3 - Bate Papo TPM #1
Battlefield 3 - Bate Papo TPM #1
::2013/07/20::
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35
TPM 1 RUSAK HARLEM SHAKE (ririn cs)
TPM 1 RUSAK HARLEM SHAKE (ririn cs)
::2013/03/15::
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36
Ayam hutan tpm 1
Ayam hutan tpm 1
::2013/03/19::
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37
20120315 ALIMENTOS QUE PREVINEM A MENOPAUSA E TPM 1
20120315 ALIMENTOS QUE PREVINEM A MENOPAUSA E TPM 1
::2012/03/19::
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38
TPM 1 1
TPM 1 1
::2012/06/22::
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39
TPM #1 Telefone
TPM #1 Telefone
::2012/10/13::
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40
Dimanche Sport : résumé EST - TPM (1-0)
Dimanche Sport : résumé EST - TPM (1-0)
::2012/10/21::
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41
TPM #1 - Supriseeeee mother fuck !!!! @MVansa
TPM #1 - Supriseeeee mother fuck !!!! @MVansa
::2013/06/23::
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42
SMK N 2 SAWAHLUNTO class 3 TPM 1/2008
SMK N 2 SAWAHLUNTO class 3 TPM 1/2008
::2013/01/15::
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43
Harlem Shake XII Tpm 1
Harlem Shake XII Tpm 1
::2013/03/15::
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44
LYON TPM 1,2 SET
LYON TPM 1,2 SET
::2013/06/04::
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45
Kerajaan Memperluaskan Bantuan Persekolahan -TPM -1
Kerajaan Memperluaskan Bantuan Persekolahan -TPM -1
::2011/10/25::
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46
040412 Filme Casal TPM 1.MPG
040412 Filme Casal TPM 1.MPG
::2012/04/07::
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47
JIL Team Glory v. TPM (1/2)
JIL Team Glory v. TPM (1/2)
::2013/06/16::
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48
TPM - 1
TPM - 1
::2013/08/30::
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49
Dancing in APIIT TPM 1
Dancing in APIIT TPM 1
::2007/04/19::
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50
TPM 1
TPM 1
::2010/12/31::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Tropomyosin 1 (alpha)

PDB rendering based on 1c1g.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TPM1 ; C15orf13; CMD1Y; CMH3; HTM-alpha; TMSA
External IDs OMIM191010 MGI98809 HomoloGene128484 GeneCards: TPM1 Gene
RNA expression pattern
PBB GE TPM1 210986 s at tn.png
PBB GE TPM1 206116 s at tn.png
PBB GE TPM1 210987 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7168 22003
Ensembl ENSG00000140416 ENSMUSG00000032366
UniProt P09493 Q545Y3
RefSeq (mRNA) NM_000366 NM_024427
RefSeq (protein) NP_000357 NP_077745
Location (UCSC) Chr 15:
63.33 – 63.36 Mb
Chr 9:
66.82 – 66.85 Mb
PubMed search [1] [2]

Tropomyosin alpha-1 chain is a protein that in humans is encoded by the TPM1 gene.[1]

This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.[2]

Interactions[edit]

TPM1 has been shown to interact with TPM2.[3]

References[edit]

  1. ^ Mogensen J, Kruse TA, Borglum AD (Jun 1999). "Refined localization of the human alpha-tropomyosin gene (TPM1) by genetic mapping". Cytogenet Cell Genet 84 (1-2): 35–6. doi:10.1159/000015207. PMID 10343096. 
  2. ^ "Entrez Gene: TPM1 tropomyosin 1 (alpha)". 
  3. ^ Brown, H R; Schachat F H (Apr 1985). "Renaturation of skeletal muscle tropomyosin: implications for in vivo assembly". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 82 (8): 2359–63. doi:10.1073/pnas.82.8.2359. ISSN 0027-8424. PMC 397557. PMID 3857586. 

Further reading[edit]

External links[edit]


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