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1
RARE CHROMOSOME DISORDER ~ Dowie living with T8M (Trisomy 8 Mosaic syndrome)
RARE CHROMOSOME DISORDER ~ Dowie living with T8M (Trisomy 8 Mosaic syndrome)
::2012/08/22::
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2
Rare Chromosome Disorder (T8M) Trisomy 8 Mosaic Syndrome
Rare Chromosome Disorder (T8M) Trisomy 8 Mosaic Syndrome
::2014/02/28::
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3
Trisomy 8 Awareness!!
Trisomy 8 Awareness!!
::2012/07/20::
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4
Lane, Full Trisomy 18 at 5 years & 8 months old, having a sit down chat with Mommy.
Lane, Full Trisomy 18 at 5 years & 8 months old, having a sit down chat with Mommy.
::2014/08/03::
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5
Kathleen Rose: Trisomy 13: How Our Beautiful Girl Surprised us all!
Kathleen Rose: Trisomy 13: How Our Beautiful Girl Surprised us all!
::2014/07/04::
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6
Edward
Edward's Syndrome(Trisomy 18)-Biology Genetic Project
::2014/05/12::
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7
Hudson Thomas Gardner // Trisomy 18 Story // Lights Camera Love
Hudson Thomas Gardner // Trisomy 18 Story // Lights Camera Love
::2014/07/05::
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8
Alexandria
Alexandria's Journey, 50 Days with us. (Trisomy 18)
::2012/02/13::
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9
Trisomy 13      My Movie  nevaeh
Trisomy 13 My Movie nevaeh
::2012/07/22::
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10
Nondisjunction (Trisomy 21) - An Animated Tutorial
Nondisjunction (Trisomy 21) - An Animated Tutorial
::2011/12/08::
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11
trisomy 18 and living {kayden}
trisomy 18 and living {kayden}
::2008/08/01::
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12
We Are The World Of Trisomy 13 & 18 -- 2012 Awareness Video .m4v
We Are The World Of Trisomy 13 & 18 -- 2012 Awareness Video .m4v
::2012/03/31::
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13
Jasper Tran Will Trisomy 18
Jasper Tran Will Trisomy 18
::2013/10/12::
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14
Trisomy 18- 22 Year Old
Trisomy 18- 22 Year Old
::2012/03/07::
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15
National Convention for Life: Tracey Harkin : My daugher Kathleen Rose has Trisomy 13
National Convention for Life: Tracey Harkin : My daugher Kathleen Rose has Trisomy 13
::2014/04/12::
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16
2012 -Our Trisomy 18 Journey  2014 Update..Our daughter is 2 now!
2012 -Our Trisomy 18 Journey 2014 Update..Our daughter is 2 now!
::2013/01/02::
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17
What is Trisomy X? 47 XXX I have this condition
What is Trisomy X? 47 XXX I have this condition
::2014/07/27::
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18
Baby Jacob Vokey - Trisomy 18
Baby Jacob Vokey - Trisomy 18
::2012/10/01::
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19
Speak Life - Journey with Mosaic Trisomy 18
Speak Life - Journey with Mosaic Trisomy 18
::2014/03/07::
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20
Wiktoria with trisomy 13 at 17 months
Wiktoria with trisomy 13 at 17 months
::2014/10/21::
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21
Trisomy Awareness Video 2011
Trisomy Awareness Video 2011
::2011/06/15::
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22
One day with William. A Trisomy 9 mosaic child.
One day with William. A Trisomy 9 mosaic child.
::2014/04/07::
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23
What is Trisomy 18?
What is Trisomy 18?
::2012/01/30::
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24
Lane, Full Trisomy 18, is now following my vocal commands at 5 1/2 years old!
Lane, Full Trisomy 18, is now following my vocal commands at 5 1/2 years old!
::2014/05/17::
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25
Mosaic Trisomy 18 - Brandon
Mosaic Trisomy 18 - Brandon's Story of Hope - Age 16 and Living Life to the Full
::2012/07/25::
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26
Lane, Full Trisomy 18 at 5 years 11 months old, playing with Mimi.
Lane, Full Trisomy 18 at 5 years 11 months old, playing with Mimi.
::2014/10/29::
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27
Abigail Hellmer Trisomy 18 Tribute Video
Abigail Hellmer Trisomy 18 Tribute Video
::2012/07/10::
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28
8/26/10 Alina mosaic trisomy 18
8/26/10 Alina mosaic trisomy 18
::2010/08/28::
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29
Baby Ian
Baby Ian's 4 days on earth with Trisomy 18
::2012/07/24::
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30
Trisomy X
Trisomy X
::2012/01/26::
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31
A trisomy time lapse morning.
A trisomy time lapse morning.
::2014/06/13::
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32
Wiktoria with trisomy 13
Wiktoria with trisomy 13
::2014/03/03::
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33
Dylan Edge Trisomy 13 mosaicism our miracle boy xx
Dylan Edge Trisomy 13 mosaicism our miracle boy xx
::2014/02/28::
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34
Lane, Full Trisomy 18, at 5 1/2 years old, is now creeping along the floor all by himself!
Lane, Full Trisomy 18, at 5 1/2 years old, is now creeping along the floor all by himself!
::2014/07/03::
Play Video
35
The World of a child with Trisomy
The World of a child with Trisomy
::2011/07/29::
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36
Teen With Mosaic Trisomy 18 Questions Dawkins
Teen With Mosaic Trisomy 18 Questions Dawkins' Down Syndrome Comments
::2014/08/26::
Play Video
37
Nolan at 2 months starting to coo! He has full trisomy 18
Nolan at 2 months starting to coo! He has full trisomy 18
::2009/08/25::
Play Video
38
Brilen Full Trisomy 13
Brilen Full Trisomy 13
::2014/03/18::
Play Video
39
Abbie Ann Johnson - Our Trisomy Story - Short Version
Abbie Ann Johnson - Our Trisomy Story - Short Version
::2014/09/08::
Play Video
40
Love, Miracles, Inspiration...Trisomy 9 faces!  2-Medium
Love, Miracles, Inspiration...Trisomy 9 faces! 2-Medium
::2013/04/01::
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41
Noah & The Many Faces of Trisomy
Noah & The Many Faces of Trisomy
::2011/03/07::
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42
Lane
Lane's Trisomy 18 Journey from birth to 20 months old.
::2010/08/23::
Play Video
43
Routine Health Care for the Trisomy 18 Child
Routine Health Care for the Trisomy 18 Child
::2013/02/25::
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44
Trisomy 18 - Dear Caitlin
Trisomy 18 - Dear Caitlin
::2011/08/09::
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45
brilen full trisomy 13   our world
brilen full trisomy 13 our world
::2014/07/26::
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46
Kayli, with Trisomy 18, splashes the water during aquatic therapy, when prompted!
Kayli, with Trisomy 18, splashes the water during aquatic therapy, when prompted!
::2013/10/22::
Play Video
47
Brooke
Brooke's Journey with Trisomy 14 Mosaic
::2014/02/28::
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48
Trinucleotide Repeat Expansion, Trisomy 21, Nuchal Translucency Alphafetoprotein t(1418) t(1517)
Trinucleotide Repeat Expansion, Trisomy 21, Nuchal Translucency Alphafetoprotein t(1418) t(1517)
::2014/06/14::
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49
Trisomy Awareness Video: What to expect when expecting a child with Trisomy
Trisomy Awareness Video: What to expect when expecting a child with Trisomy
::2012/04/10::
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50
Lane @ 29 months w/ Full Trisomy 18 is now able to pull himself up into a crawl position
Lane @ 29 months w/ Full Trisomy 18 is now able to pull himself up into a crawl position
::2011/05/23::
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RESULTS [51 .. 101]
From Wikipedia, the free encyclopedia
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Not to be confused with Warkany syndrome 1.
Trisomy 8
Classification and external resources
Chromosome 8.svg
ICD-10 Q92
ICD-9 758
DiseasesDB 32656
MeSH D014314

Trisomy 8, also known as Warkany syndrome 2,[1] is a human chromosomal disorder caused by having three copies (trisomy) of chromosome 8. It can appear with or without mosaicism.

Characteristics[edit]

Complete trisomy 8 causes severe effects on the developing fetus and can be a cause of miscarriage.[2] Complete trisomy 8 is usually an early lethal condition, whereas trisomy 8 mosaicism is less severe and individuals with a low proportion of affected cells may exhibit a comparatively mild range of physical abnormalities and developmental delay.[3][4] Individuals with trisomy 8 mosaicism are more likely to survive into childhood and adulthood, and exhibit a characteristic and recognizable pattern of developmental abnormalities. Common findings include retarded psychomotor development, moderate to severe mental retardation, variable growth patterns which can result in either abnormally short or tall stature, an expressionless face, and many musculoskeletal, visceral, and eye abnormalities, as well as other anomalies.[5] A deep plantar furrow is considered to be pathognomonic of this condition, especially when seen in combination with other associated features.[6] The type and severity of symptoms are dependent upon the location and proportion of trisomy 8 cells compared to normal cells.

Other conditions[edit]

Trisomy 8 mosaicism affects wide areas of chromosome 8 containing many genes, and can thus be associated with a range of symptoms.

References[edit]

  1. ^ DDB 32656
  2. ^ Riccardi VM (1977). "Trisomy 8: an international study of 70 patients". Birth Defects Orig. Artic. Ser. 13 (3C): 171–84. PMID 890109. 
  3. ^ Jones, K. L. (2005). Smith's Recognizable Patterns of Human Malformation. (6th ed.). Philadelphia: W. B. Sanders Company.
  4. ^ Jones, K. L. (2005). Smith's Recognizable Patterns of Human Malformation. (6th ed.). Philadelphia: W. B. Sanders Company.
  5. ^ Riccardi VM (1977). "Trisomy 8: an international study of 70 patients". Birth Defects Orig. Artic. Ser. 13 (3C): 171–84. PMID 890109. 
  6. ^ Lai CC (1975). "Trisomy 8 syndrome". Clin. Orthop. Relat. Res. 110: 238–43. PMID 1157389. 
  7. ^ "MIM ID #268400 ROTHMUND-THOMSON SYNDROME; RTS". NCBI/OMIM. 
  8. ^ "MIM ID *134450 FACTOR VII REGULATOR; F7R". NCBI/OMIM. 
  9. ^ "MIM ID #190350 TRICHORHINOPHALANGEAL SYNDROME, TYPE I; TRPS1". NCBI/OMIM. 
  10. ^ "MIM ID #179613 RECOMBINANT CHROMOSOME 8 SYNDROME". NCBI/OMIM. 

External links[edit]

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