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U.S. Route 50 marker

U.S. Route 50
Route information
Maintained by IDOT
Length 165.79 mi[1] (266.81 km)
Existed 1926 – present
Major junctions
West end US 50 / I-255 in Columbia
  I-64 / I-255 in Washington Park
I-64 / IL 158 in O'Fallon
US 51 in Sandoval
I-57 in Salem
US 45 in Flora
East end US 50 in Lawrenceville
Highway system
IL 49 IL 50

In the U.S. state of Illinois, U.S. Route 50 is an east–west highway across the southern portion of the state. It runs from the Jefferson Barracks Bridge over the Mississippi River to Missouri east to the Red Skelton Memorial Bridge over the Wabash River to Indiana. This is a distance of 165.79 miles (266.81 km).[1]

Route description[edit]

U.S. 50 runs east–west across the southern portion of the state, between Interstate 70 to the north and Interstate 64 to the south. Along many portions of U.S. 50, the road has been moved onto either a bypass or an expressway.


Much of U.S. Route 50 in Illinois, especially the section between Carlyle, Illinois and Vincennes, lies atop or adjacent to the trail taken by George Rogers Clark and his 170 volunteers in the forlorn-hope march on Vincennes in February 1779.

As of 2011, much of U.S. 50 is a two-lane highway, but portions around Lawrenceville, IL and Vincennes, IN are configured as a four-lane, limited access bypass, built to interstate standards in the 1960s. Another modern bypass portion between O'Fallon, IL and IL-127 shows evidence of a four-lane right of way as each bridge is paralleled by a second that remains unused and the graded road bed for additional lanes is visible. This is because it was originally meant to be the route of Interstate 64 until political leaders lobbied for and secured a more southerly route.

Major intersections[edit]

County Location mi[2] km Destinations Notes
Mississippi River 0.00 0.00 I-255 / US 50 continuation into Missouri
Monroe 2.9 4.7 IL 3 south Southern end of IL 3 concurrency
St. Clair 7.2 11.6 IL 3 north – Cahokia Northern end of IL 3 concurrency
9.5 15.3 IL 157
East St. Louis 13.3 21.4 IL 15
16.6 26.7 I-64 west / I-255 north – St. Louis, Chicago Northern end of I–255 concurrency; western end of I–64 concurrency
Fairview Heights 17.9 28.8 IL 157
21.4 34.4 IL 159
O'Fallon 28.1 45.2 I-64 east / IL 158 Eastern end of I–64 concurrency
Lebanon 32.9 52.9 IL 4 south – Mascoutah Southern end of IL 4 concurrency
33.5 53.9 IL 4 north Northern end of IL 4 concurrency
Clinton Trenton 40.1 64.5 IL 160
Carlyle 57.2 92.1 IL 127 north Northern end of IL 127 concurrency
58.3 93.8 IL 127 south Southern end of IL 127 concurrency
Marion Sandoval 72.4 116.5 US 51 south – Centralia Southern end of US 51 concurrency
72.6 116.8 US 51 north – Vandalia Northern end of US 51 concurrency
Salem 80.4 129.4 I-57 – Mt. Vernon, Effingham
81.8 131.6 IL 37 – Mt. Vernon, Effingham
Clay Flora 106.7 171.7 US 45 north – Effingham Western end of US 45 concurrency
110.6 178.0 US 45 south – Fairfield Eastern end of US 45 concurrency
Richland 120.9 194.6 IL 250 east Western terminus of IL 250
Olney 129.6 208.6 IL 250 west / IL 130 Western end of IL 250 concurrency
Lawrence 142.2 228.8 IL 250 east Eastern end of IL 250 concurrency
Lawrenceville 151.0 243.0
US 50 Bus. east
Western terminus of US 50 BUS
152.2 244.9 IL 1 – Lawrenceville, Marshall
154.7 249.0
US 50 Bus. west
Eastern terminus of US 50 BUS
159.5 256.7 IL 33 north Southern terminus of IL 33
165.79 266.81 US 50 east Indiana state line
1.000 mi = 1.609 km; 1.000 km = 0.621 mi


Route map: Google

KML is from Wikidata
  1. ^ a b Illinois Technology Transfer Center (2007). "T2 GIS Data". Retrieved 2007-11-08. 
  2. ^ Google (March 19, 2017). "Overview Map of US 50" (Map). Google Maps. Google. Retrieved March 19, 2017. 

U.S. Route 50
Previous state:
Illinois Next state:


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